Ovarian Dysgerminoma

Lazebnik, Noam; Balog, Anna; Bennett, Shirley L.; Redline, Raymond W.; Liu, James H.

doi:10.7863/jum.2009.28.10.1409

Cited by 22 publications

(7 citation statements)

References 12 publications

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“…In particular, dysgerminoma appear as large lobulated solid tumor with prominent fibrovascular core and minimal necrosis ( Fig. 19 ) [ 49 ].…”

Section: Solid Tumormentioning

confidence: 99%

Ultrasonography of ovarian masses using a pattern recognition approach

Jung

2015

Ultrasonography

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As a primary imaging modality, ultrasonography (US) can provide diagnostic information for evaluating ovarian masses. Using a pattern recognition approach through gray-scale transvaginal US, ovarian masses can be diagnosed with high specificity and sensitivity. Doppler US may allow ovarian masses to be diagnosed as benign or malignant with even greater confidence. In order to differentiate benign and malignant ovarian masses, it is necessary to categorize ovarian masses into unilocular cyst, unilocular solid cyst, multilocular cyst, multilocular solid cyst, and solid tumor, and then to detect typical US features that demonstrate malignancy based on pattern recognition approach.

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“…In particular, dysgerminoma appear as large lobulated solid tumor with prominent fibrovascular core and minimal necrosis ( Fig. 19 ) [ 49 ].…”

Section: Solid Tumormentioning

confidence: 99%

Ultrasonography of ovarian masses using a pattern recognition approach

Jung

2015

Ultrasonography

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“…Diagnosing ovarian germ cell tumors is challenging [5]. Following clinical examination and imaging tests (ultrasound, CT and magnetic resonance imaging (MRI)), the finding of increased serum levels of β-hCG, α-FP and LDH suggest the diagnosis pre-operatively.…”

Section: Discussionmentioning

confidence: 99%

Ovarian dysgerminoma and synchronic contralateral tubal pregnancy followed by normal intra-uterine gestation: a case report

et al. 2012

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IntroductionWe report that the coincidence of ovarian tumor and pregnancy poses significant challenges that are more pronounced if the pregnancy is ectopic.Case presentationHere, we report a rare and interesting case of a 24-year-old nulliparous Spanish woman who experienced the coincidental occurrence of left tubal pregnancy and dysgerminoma in the right ovary. The corpus luteum settled in the right ovary. A right adnexectomy and left linear salpingostomy were performed. Remarkably, our patient became pregnant spontaneously after surgery. The pregnancy occurred prior to starting chemotherapy, and the intra-uterine pregnancy was carried to term; later, she also had another normal pregnancy. Our patient has done well without chemotherapy.ConclusionsOur report on the challenges of diagnosis and treatment faced in this case can help clinicians better understand and manage these pathologies. We have not found any similar cases in the literature.

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“…At Doppler ultrasonography, they are abundantly vascularized at power and color. [ 37 – 39 ] In our study, ultrasound results show unclear boundaries, component lobules, with heterogeneous echogenicity. This feature suggests that the mass may be malignant.…”

Section: Discussionmentioning

confidence: 48%

Pregnancy with giant ovarian dysgerminoma

Zhang¹,

Zhai

Huang³

et al. 2020

Medicine

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Rationale: Dysgerminoma is an extraordinarily rare neoplasm arising from the malignant germ cells of the ovary. Early antenatal diagnosis and proper management of the neoplasm to improve maternal-neonatal results are the considerable challenges facing the gyne-oncologist. We summarize the clinical features and discuss treatment strategies of the ovary dysgerminoma (OD). Besides, we also review the literature on OD in PubMed, Web of Science Core Collection, Library of Congress, and LISTA from 1939 to 2019 to evaluate its clinical characteristics, feto-maternal compromise, management, and fertility outcome. Patient concerns: A 25-year-old pregnant woman reported lower abdominal pain and vomiting. Diagnosis: The patient was diagnosed as right OD. Interventions: She received a cesarean section due to severe abdominal pain, delivered a healthy girl at 38 C 4 weeks of gestation, and accepted fertility-preserving surgery. However, the patient refused chemotherapy postoperatively. Outcomes: The patient was followed up 42 days, 3 months, and 6 months after surgery, and no tumor recurrence was observed. Lessons: OD has non-specificity characteristics, including age, symptoms, image date, and tumor marks. However, these abnormal indicators may provide some evidence for accurate antenatal diagnosis. The management strategies should be considered comprehensively on an individual basis, and fertility-preserving surgery should be carried out in the second trimester if further pregnancy is desired. Adjuvant chemotherapy needs to be applied to the treatment of OD patients with The International Federation of Gynecology and Obstetrics (FIGO) stages II, III, and IV and timely chemotherapy is suggested if there are several weeks before the expected date of delivery. The overall prognosis of OD patients is excellent.

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Ovarian Dysgerminoma

Cited by 22 publications

References 12 publications

Ultrasonography of ovarian masses using a pattern recognition approach

Ultrasonography of ovarian masses using a pattern recognition approach

Ovarian dysgerminoma and synchronic contralateral tubal pregnancy followed by normal intra-uterine gestation: a case report

Pregnancy with giant ovarian dysgerminoma

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