Ovarian haemangiomas and stromal luteinization

Abstract

Figure 3 . a The papillary component was positive for thyroglobulin. whereas b the medulbdry areas stained for calcitonin. References 1. Albores-Saavedra J. IlVolsi VA. Williams ED. Medullary carcinoma. Sem. Diagn. Puthol. 1985: 2; 137-146. 2. Rosai 1. Carcangiu ML. DeLellis RA. Tumors of the thyroid gland. Atlas o/ Tumor Pathology. Washington, DC: Armed Forces Institute of Pathology, 1992. 3. Sobrinho-SimBes M. Mixed medullary and follicular carcinoma of the thyroid. Histopathology 1993: 23: 287-289. 4. Tanda F. Massarelli G. Mingioni V. Bosincu I-. Moroni RV. Cossu A.Mixed follicular -parafollicular carcinoma of the thyroid: a light, electron microscopic and histoimmunologic study. Surg. Pathol. 1990: 3; 65-74, 5.Albores-Saavedra J. Gorraez da la Mom T. de la Torre-Rendon F.Gould E. Mixed medullary-papillary carcinoma of the thyroid a previously unrecognized variant of thyroid carcinoma. Hum.

Ovarian teratoma showing a predominant hemangiomatous element with stromal luteinization: Report of a case and review of the literature

“…Except for these dermoid elements, these tumors were very similar to each other. Similarly, the histological characteristics of the present case were obviously similar with those of cases previously reported as ovarian hemangiomas showing stromal luteinization, 6–9 except for the coexistence of a small cyst lined by respiratory epithelium. However, most of the reported cases were diagnosed as ovarian hemangiomas, although the hemangiomatous lesion can not be distinguishable from that of the present case.…”

“…We herein report a case of ovarian teratoma showing a predominant hemangiomatous element with stromal luteinization. Histological characteristics in the present case were obviously similar with those of cases previously reported as ovarian hemangiomas showing stromal luteinization, 6–9 except for the coexistence of a small portion of teratomatous components.…”

“…The presence of these luteinized cells in a close and presumably causal relationship with the benign vascular lesion is intriguing for one more reason: because it was found in a postmenopausal woman. Five out of six reported cases of ovarian hemangioma with stromal luteinization, and the present case, were also postmenopausal women 6–9 . Postmenopausal bleeding and inappropriate proliferative endometrium with complex hyperplasia may manifest hyperestrogenism.…”

“…Stromal luteinization is most frequently seen in pregnancy but is also a common reaction to various epithelial, germ cell and metastatic neoplasms 6 . The presence of these luteinized cells in a close and presumably causal relationship with the benign vascular lesion is intriguing for one more reason: because it was found in a postmenopausal woman.…”

“…Ovarian teratoma with hemangiomatous differentiation is poorly recognized and only two cases have been reported, 1,2 because the hemangiomatous elements are not usually included in the spectrum of teratomatous tissues found in ovarian teratoma 3,4 . In contrast, pure ovarian hemangioma is also rare, but is documented better than teratoma with hemangiomatous elements, and 40 or more cases have been reported in English literature 4–9 . However, their origin, whether a monodermal teratoma or a true soft tissue‐type neoplasm arising in the ovarian stroma, has not been elucidated to date.…”