Overcoming barriers to diabetes control in geriatrics

Hammouda, Emad I.

doi:10.1111/j.1742-1241.2010.02599.x

International Journal of Clinical Practice

2011

DOI: 10.1111/j.1742-1241.2010.02599.x

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Overcoming barriers to diabetes control in geriatrics

Emad I. Hammouda

Abstract: There is a need for extra care and overcoming barriers to diabetes control in old patients as a dynamic and a continuous task that needs coordination of healthcare systems and professionals at all levels of care.

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Cited by 5 publications

(1 citation statement)

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“…The residual risk is enhanced by inadequate remediation of multiple risk factors 20–22 and poor treatment adherence to multidrug regimens. 23,24 Improved use of evidence-based therapy in the United States have been accompanied by reductions in CVD events. 25 …”

mentioning

confidence: 99%

Modulating peroxisome proliferator–activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects

Rosenson

Wright

Farkouh

et al. 2012

American Heart Journal

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Clinical trials of cardiovascular disease (CVD) prevention in patients with type 2 diabetes mellitus primarily have been directed at the modification of a single major risk factor; however, in trials that enroll patients with and without diabetes, the absolute risk in CVD events remains higher in patients with diabetes. Efforts to reduce the macrovascular and microvascular residual risk have been directed toward a multifactorial CVD risk-factor modification; nonetheless, long-term complications remain high. Dual-peroxisome proliferator–activated receptor (PPAR) α/γ agonists may offer opportunities to lower macrovascular and microvascular complications of type 2 diabetes mellitus beyond the reductions achieved with conventional risk-factor modification. The information presented elucidates the differentiation of compound-specific vs class-effect properties of PPARs as the basis for future development of a new candidate molecule. Prior experience with thiazolidinediones, an approved class of PPARγ agonists, and glitazars, investigational class of dual-PPARα/γ agonists, also provides important lessons about the risks and benefits of targeting a nuclear receptor while revealing some of the future challenges for regulatory approval.

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mentioning

confidence: 99%

Modulating peroxisome proliferator–activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects

Rosenson

Wright

Farkouh

et al. 2012

American Heart Journal

View full text Add to dashboard Cite

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Insulintherapie im Alter – eine qualitative Versorgungsstudie

Grundke

Klement

2018

GGP

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Zusammenfassung Herausforderungen Eine effektive Verzahnung der Kooperation von Versorgungsebenen und Leistungserbringern hat zentrale Bedeutung für niedrige Hospitalisierungsraten sowie bedarfsgerechte medizinische und pflegerische Versorgung älterer insulinpflichtiger Typ-2-Diabetiker.1 Die zentralen Herausforderungen der berufsgruppenübergreifenden Zusammenarbeit bestehen darin, die Insulintherapie nicht nur an Stoffwechselzielen zu orientieren, sondern ebenso die Patientensicherheit, ökonomische Effizienz und individuelle Lebensqualitätsvorstellungen von Patienten und deren Angehörigen zu berücksichtigen. 1–3

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Insulintherapie im Alter

Grundke

Klement

2018

Diabetes aktuell

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ZUSAMMENFASSUNGEine effektive Verzahnung der Kooperation von Versorgungsebenen und Leistungserbringern hat zentrale Bedeutung für niedrige Hospitalisierungsraten sowie bedarfsgerechte medizinische und pflegerische Versorgung älterer insulinpflichtiger Typ-2-Diabetiker 1. Die zentralen Herausforderungen der berufsgruppenübergreifenden Zusammenarbeit bestehen darin, die Insulintherapie nicht nur an Stoffwechselzielen zu orientieren, sondern ebenso die Patientensicherheit, ökonomische Effizienz und individuelle Lebensqualitätsvorstellungen von Patienten und deren Angehörigen zu berücksichtigen 1–3.

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Overcoming barriers to diabetes control in geriatrics

Abstract: There is a need for extra care and overcoming barriers to diabetes control in old patients as a dynamic and a continuous task that needs coordination of healthcare systems and professionals at all levels of care.

Cited by 5 publications

References 18 publications

Modulating peroxisome proliferator–activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects

Modulating peroxisome proliferator–activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects

Insulintherapie im Alter – eine qualitative Versorgungsstudie

Insulintherapie im Alter

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