Overcoming limitations in diffusion‐weighted MRI of breast by spatio‐temporal encoding

Solomon, Eddy; Nissan, Noam; Furman‐Haran, Edna; Seginer, Amir; Shapiro-Feinberg, Myra; Degani, Hadassa; Frydman, Lucio

doi:10.1002/mrm.25344

Cited by 26 publications

(28 citation statements)

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“…However, FSE techniques also come with drawbacks of increased T2-weighted signal loss and blurring and additional RF heating, and require further technical optimizations. A number of other emerging non-EPI approaches also show promise for overcoming current image quality challenges of breast DWI [61, 62], but are in earlier stages of development.…”

Section: Advanced Techniquesmentioning

confidence: 99%

DWI in the Assessment of Breast Lesions

Partridge

Amornsiripanitch

2017

Topics in Magnetic Resonance Imaging

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Diffusion-weighted MRI (DWI) holds promise to address some of the shortcomings of routine clinical breast MRI and to expand the capabilities of imaging in breast cancer management. DWI reflects tissue microstructure, and provides unique information to aid in characterization of breast lesions. Potential benefits under investigation include improving diagnostic accuracy and guiding treatment decisions. As a result, DWI is increasingly being incorporated into breast MRI protocols and multicenter trials are underway to validate single institution findings and to establish clinical guidelines. Advancements in DWI acquisition and modeling approaches are helping to improve image quality and extract additional biologic information from breast DWI scans, which may extend diagnostic and prognostic value.

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Section: Advanced Techniquesmentioning

confidence: 99%

DWI in the Assessment of Breast Lesions

Partridge

Amornsiripanitch

2017

Topics in Magnetic Resonance Imaging

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“…As a consequence, it requires a dedicated formalism for analyzing these diffusion-weighted SPEN (dSPEN) data, which takes into account the concomitant effects of adiabatic pulses, of the imaging as well as diffusion gradients, and of the cross-terms between them. The method is currently under experimental validations in phantom systems, but very promising in vivo results have been achieved in the breast [196]. Recent 3-T clinical scanners are also equipped with dual RF transmission sources.…”

Section: Perspectives: Multi-slice Imaging and Multi-transmitmentioning

confidence: 97%

State-of-the-art MRI techniques in neuroradiology: principles, pitfalls, and clinical applications

et al. 2015

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This article reviews the most relevant state-of-the-art magnetic resonance (MR) techniques, which are clinically available to investigate brain diseases. MR acquisition techniques addressed include notably diffusion imaging (diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI), and diffusion kurtosis imaging (DKI)) as well as perfusion imaging (dynamic susceptibility contrast (DSC), arterial spin labeling (ASL), and dynamic contrast enhanced (DCE)). The underlying models used to process these images are described, as well as the theoretic underpinnings of quantitative diffusion and perfusion MR imaging-based methods. The technical requirements and how they may help to understand, classify, or follow-up neurological pathologies are briefly summarized. Techniques, principles, advantages but also intrinsic limitations, typical artifacts, and alternative solutions developed to overcome them are discussed. In this article, we also review routinely available three-dimensional (3D) techniques in neuro MRI, including state-of-the-art and emerging angiography sequences, and briefly introduce more recently proposed 3D quantitative neuro-anatomy sequences, and new technology, such as multi-slice and multi-transmit imaging.

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“…Finally, from the resulting high‐definition diffusion‐weighted images, ADC/DTI maps were computed after accounting for the effects of both the imaging and the diffusion gradients onto the b‐tensor along the lines described in Refs. [45, 46].…”

Section: Methodsmentioning

confidence: 99%

A regularized reconstruction pipeline for high‐definition diffusion MRI in challenging regions incorporating a per‐shot image correction

Cousin

Liberman

Solomon

et al. 2019

Magnetic Resonance in Med

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Purpose Diffusion MRI is of interest for clinical research and diagnosis. Whereas high‐ resolution DWI/DTI is hard to achieve by single‐shot methods, interleaved acquisitions can deliver these if motion and/or folding artefacts are overcome. Thanks to its ability to provide zoomed, folding‐free images, spatially encoded MRI can fulfill these requirements. This is here coupled with a regularized reconstruction and parallel receive methods, to deliver a robust scheme for human DWI/DTI at mm and sub‐mm resolutions. Methods Each shot along the spatially encoded dimension was reconstructed separately to retrieve per‐shot phase maps. These shots, together with coil sensitivities, were combined with spatially encoded quadratic phase‐encoding matrices associated to each shot, into single global operators. Their originating images were then iteratively computed aided by l1 and l2 regularization methods. When needed, motion‐corrupted shots were discarded and replaced by redundant information arising from parallel imaging. Results Full‐brain DTI experiments at 1 mm and restricted brain DTIs with 0.75 mm nominal in‐plane resolutions were acquired and reconstructed successfully by the new scheme. These 3 Tesla spetiotemporally encoded results compared favorably with EPI counterparts based on segmented and selective excitation schemes provided with the scanner. Conclusion A new procedure for achieving high‐definition diffusion‐based MRI was developed and demonstrated.

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Overcoming limitations in diffusion‐weighted MRI of breast by spatio‐temporal encoding

Abstract: SPEN-based sequences yielded diffusion-weighted breast images with minimal artifacts and distortions, enabling the calculation of improved ADC maps and the identification of decreased ADCs in malignant regions.

Cited by 26 publications

References 50 publications

DWI in the Assessment of Breast Lesions

DWI in the Assessment of Breast Lesions

State-of-the-art MRI techniques in neuroradiology: principles, pitfalls, and clinical applications

A regularized reconstruction pipeline for high‐definition diffusion MRI in challenging regions incorporating a per‐shot image correction

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