2001
DOI: 10.1080/j.1600-0412.2001.080008719.x
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Oxidative stress in pre-eclampsia

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Cited by 27 publications
(44 citation statements)
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“…Serum MDA mainly results from the oxidation of cell membrane and lipoprotein lipid contents that are rich in polyunsaturated fatty acids [34]. Several authors [3,5,[12][13][14], but not all [45], reported increased serum MDA levels in preeclampsia. In a recent study [11] that was carried out in our laboratories, MDA level was determined by a spectrophotometric method, and in the present study, MDA level was determined by HPLC that has been accepted as a more specific technique for MDA measurements.…”
Section: Discussionmentioning
confidence: 99%
“…Serum MDA mainly results from the oxidation of cell membrane and lipoprotein lipid contents that are rich in polyunsaturated fatty acids [34]. Several authors [3,5,[12][13][14], but not all [45], reported increased serum MDA levels in preeclampsia. In a recent study [11] that was carried out in our laboratories, MDA level was determined by a spectrophotometric method, and in the present study, MDA level was determined by HPLC that has been accepted as a more specific technique for MDA measurements.…”
Section: Discussionmentioning
confidence: 99%
“…These patients had significantly higher levels of thiobarbituric acid reactive substances (TBARS) than the control subjects (P Ͻ.001) and patients with preeclampsia (P Ͻ.01) (29). Bowen et al found significantly higher levels of cord blood MDA in patients with eclampsia (30). The studies by Diedrich et al and Bowen et al suggest that oxidative stress increases with the severity of HELPP syndrome and eclampsia.…”
Section: Lipid Peroxidation: Role In Preeclampsiamentioning
confidence: 95%
“…The resultant abnormal intrauterine milieu restricts the supply of crucial nutrients to the fetus, thereby limiting fetal growth. Multiple studies have shown that intrauterine growth retardation is associated with increased oxidative stress in the human fetus [73][74][75][76][77][78][79][80]. A major consequence of limited nutrient availability is an alteration in the redox state in susceptible fetal tissues leading to oxidative stress.…”
Section: Cellular Mechanisms: Mitochondrial Dysfunction and Oxidativementioning
confidence: 99%