Oxygen, carbon dioxide, and hydrogen ion concentrations in arterial blood during pregnancy

Blechner, Jack N.; Cotter, Julian R.; Stenger, Vincent G.; Hinkley, Clark M.; Prystowsky, Harry

doi:10.1016/s0002-9378(15)33631-0

Cited by 33 publications

(14 citation statements)

References 4 publications

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“…Other investigators reported higher pa0 2 levels in pregnancy but stated that pa0 2 'did not increase äs much äs expected from hyperventilation [23,30]. We found that the mean pa0 2 is increased in normal pregnancy over nonpregnant values (99.3 vs 95.0 Torr), in agreement with the more recent reports [l, 3,28]. The higher paQ 2 values obtained in our study, äs well äs the latter studies, compared to the previous hyperventilation) stimulates the enzyme phosphostudies, are probably due to the use of the sen-fructo-kinase that results in increased glycolytic sitive direct polarographic technique for the production of pyruvate and consequently lactate measurement of the oxygen tension.…”

Section: Discussionsupporting

confidence: 92%

“…The mean pH wasfound [29]. These bands show, with 95% confidence, to be 7.42 ± 0.03, in close agreement with others these relationships in simple acid-base disturb- [1,3,6,15,24]. Thisvalue, which corresponds to an ces .…”

Section: Discussionsupporting

confidence: 80%

“…However, the studies that pregnancy [28]. were conducted during cesarean section to The mean paC0 2 in this study was 28.8 ± 3.7 Torr, determine the directional transfer of lactate and Others reported the same [3] or alowervalue [7], pynwate across the placenta are conflicting and but mostly a slightly higher paC0 2 [1,4,6,15,24]. non-conclusive [8,13,18].…”

Section: Discussionmentioning

confidence: 57%

“…At least some of these discrepancies are due to differences in blood sampling methods and laboratory techniques. In some studies, the blood specimens were either venous or capillary [7,15,24], while in.others [l, 3,6], äs in this study, arterial blood specimens were utilized. The control non-pregnant values are in close agreement with those cited in previous reports [14,29].…”

Section: Discussionmentioning

confidence: 99%

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Normal pregnancy: A model of sustained respiratory alkalosis

Fadel¹,

Northrop²,

Misenhimer³

et al. 1979

Journal of Perinatal Medicine

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 57%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Normal pregnancy: A model of sustained respiratory alkalosis

Fadel¹,

Northrop²,

Misenhimer³

et al. 1979

Journal of Perinatal Medicine

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“…The normal range of arterial gases at term pregnancy has been studied previously, with a wide variety of results. Arterial oxygen tensions have been reported to be normal, low and high [11][12][13]. The mechanism for the supine fall in PaO 2 in our pregnant women at the second and third trimester is not clear.…”

Section: Discussionmentioning

confidence: 86%

Effect of Body Position on PaO<sub>2</sub> and PaCO<sub>2 </sub>during Pregnancy

Spiropoulos

Prodromaki

Tsapanos

2004

Gynecol Obstet Invest

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Background: The body position may have an effect on gas exchange though the magnitude of this effect has not been studied thoroughly during the three trimesters of pregnancy. Objectives: This study analyzes the effect of body position change on arterial oxygen tension (PaO₂) and arterial carbon dioxide tension (PaCO₂) in healthy pregnant women. Methods: We examined 21 lung healthy pregnant women at the end of the first, second and third trimester of pregnancy. Blood was drawn from the radial artery first in the sitting and subsequently in the supine position. Peak expiratory flow rate was determined as well. Results: No statistically significant difference was detected between the mean values of PaO₂ in the supine and in the sitting position at the end of the first trimester. On the contrary, at the end of the second trimester the mean value of PaO₂ in the supine position was 92.39 ± 1.95 mm Hg, while in the sitting position the mean PaO₂ was 96.56 ± 1.83 mm Hg (p < 0.001). At the end of the third trimester the mean PaO₂ in the supine position was 90.48 ± 2.91 mm Hg while in the sitting position the mean PaO₂ was 97.48 ± 1.46 mm Hg (p < 0.001). Conclusions: According to our data we conclude that the statistically significant difference in PaO₂ in the sitting and supine positions clearly shows that the position needs to be considered both when attempting to establish reference values and when evaluating gas tensions at the end of pregnancy.

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Maternal Changes in Pregnancy

Eldrtdge¹

2002

Anaesthesia for Obstetrics and Gynaecology

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Oxygen, carbon dioxide, and hydrogen ion concentrations in arterial blood during pregnancy

Cited by 33 publications

References 4 publications

Normal pregnancy: A model of sustained respiratory alkalosis

Normal pregnancy: A model of sustained respiratory alkalosis

Effect of Body Position on PaO<sub>2</sub> and PaCO<sub>2 </sub>during Pregnancy

Maternal Changes in Pregnancy

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