Oxygen reserve index guided oxygen titration in one lung ventilation with low fresh gas flow

Abstract

Background/aim: Continuous oxygen reserve index (ORI) measurement with multiple wave pulse co-oximetry is a noninvasive measurement. The decrease in the ORI trend provides a prediction for the development of hypoxemia and provides information on hyperoxia. Our aim is to determine the effect of ORI-guided oxygen titration on hyperoxemia-mediated morbidity. Materials and methods:Consecutive 120 ASA I-III patients, 18-70 years of age, without severe obstruction or restriction, undergoing one lung ventilation (OLV), were included in the study. Patients were divided into 4 groups. Oxygen titration without ORI monitoring with low-flow anesthesia (1 L/min, Group 1, n=25) and high-flow anesthesia (4 L/min, Group 2, n=28). Oxygen titration by ORI monitoring with low flow anesthesia (1 L/min, Group 3, n=25) and high flow anesthesia (4 L/min, Group 4, n=25). FiO2 increased up to 100% if necessary. OLV time, duration of surgery and anesthesia, FiO2 applied during OLV, oxygen application time (T) over 60%, vital signs, hospital and ICU stay time and complications were recorded. Results:There was a statistically significant difference in terms of FiO2 used during OLV (p< 0.05).There was no difference in ORI values (p <0.05). In Group 3, both PaO2 and SpO2 were significantly lower than the others both before and during OLV.There was no significant difference in terms of ORI parameters between low flow and high flow anesthesia groups. There was a strong, positive correlation between the duration of hospital stay and FiO2 used above 80% during OLV. Conclusions:We concluded that ORI-guided thoracic anesthesia may reduce hospital stay and increase patient safety.

Determination of the incidence of hyperoxia and the effectiveness of oxygen reserve index guided FiO2 titration in preventing hyperoxia.

“…In another study investigating the effects of ORi-guided oxygen titration and hyperoxemia-mediated morbidity in one-lung ventilation, lower mean FiO 2 and PaO 2 values with ORi monitoring were reported. They concluded that in thoracic anesthesia, ORi-guided oxygen titration can protect from hyperoxia, reduce the length of hospital stay, and increase patient safety (24). In parallel with our study, these studies stated that ORi has a bene cial role in preventing hyperoxia and achieving optimum oxygenation with its guiding effect on FiO 2 titration.…”

Usefulness of oxygen reserve index (ORi) in clinical practice

“…As a result, patients with ORi monitoring had lower PaO 2 values than patients without additional ORi monitoring. Saraçoğlu et al thus demonstrated that ORi monitoring could prevent the risk of hyperoxia in patients, and in this way shorten their postoperative stay in hospital [68].…”

“…The usefulness of ORi monitoring was also studied during one-lung ventilation (OLV) in patients undergoing thoracic surgery [65][66][67][68][69]. Koishi et al demonstrated that there was a significant correlation between the ORi and PaO 2 during OLV.…”