Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function

Franchini, Maria Luísa; Athanazio, Rodrigo Abensur; Amato-Lourenço, Luís Fernando; Carreirão-Neto, Waldir; Saldiva, Paulo Hilário Nascimento; Lorenzi-Filho, Geraldo; Rubin, Bruce K.; Nakagawa, Naomi Kondo

doi:10.1016/j.chest.2016.03.035

Cited by 21 publications

(36 citation statements)

References 22 publications

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“…However, the study of Franchini et al. () showed that unheated bubble humidification does not humidify inspired oxygen to prevent deterioration of mucociliary clearance, mucus hydration and pulmonary function; this may support the finding that humidification performed no better than non‐humidification, which is consistent with Andres's results (Andres et al., ). Yang et al.…”

Section: Discussionsupporting

confidence: 61%

“…Two studies (Andres et al., ; Franchini et al., ) reported the incidence of cough after oxygen administration; the summary OR on the incidence of cough was 0.80 (95% CI: 0.42–1.52), with no evidence of heterogeneity ( p = .17, I 2 = 6%) (Figure c).…”

Section: Resultsmentioning

confidence: 97%

“…Among them, some studies reported quasi‐randomization methods, such as assigning patients into non‐humidified oxygen group or humidified group according to the odd or even property of admission date (Chen & Guo, ; Chen, Huang, Peng, & Xiao, ). In general, sequentially numbered, opaque, sealed envelopes were assigned to each participant to avoid selective bias; only four RCTs (Andres et al., ; Franchini et al., ; Liu & Chen, ; Zeng, Wang, Guo, & Huang, ) described adequate allocation concealments. Adequate blinding, which is adopted for personnel, participants and outcome assessment, is used to prevent against bias.…”

Section: Resultsmentioning

confidence: 99%

“…The routinely used cold bubble humidification for oxygen administration may not actually work (Vargas & Esquinas, ). A recent critical study (Franchini et al., ) demonstrated that the cold bubble humidification does not humidify inspired oxygen at all and offers no benefits in the promotion of mucociliary clearance, mucus hydration and pulmonary function. Therefore, many related guidelines (Aarc ; O'Driscoll et al., ; O'Driscoll et al., 1995) have recommended the direct use of non‐humidified oxygen in low‐flow oxygen therapy.…”

Section: Discussionmentioning

confidence: 99%

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Is humidified better than non‐humidified low‐flow oxygen therapy? A systematic review and meta‐analysis

Wen

Wang

Zhang

et al. 2017

Journal of Advanced Nursing

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Section: Discussionsupporting

confidence: 61%

Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Is humidified better than non‐humidified low‐flow oxygen therapy? A systematic review and meta‐analysis

Wen

Wang

Zhang

et al. 2017

Journal of Advanced Nursing

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“…ın the study by Franchini et al, cold bubble humidification did not prevent slowing of mucociliary clearance, mucus dehydration, and worsening pulmonary function; cold bubble humidification performed no better than no humidification (13).…”

Section: Humidification Therapy In Copd Patientsmentioning

confidence: 99%

Humidification therapy; long-term effects in COPD and OSAS patients

2018

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Internal Temperature of Neonatal Endotracheal Tube Predicted by Infrared Thermography: A Neonatal Bench Study

Hamada,

Hirakawa,

Tanabe

et al. 2024

Pediatric Pulmonology

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IntroductionNeonatal ventilators are managed by monitoring the inspiratory gas temperature with a probe placed outside the incubator, although the temperature decreases as the gases passe through the ventilator circuit extension tube and endotracheal tube (ETT). There are no established methods for measuring the internal temperature of the ETT. This bench study aimed to investigate the feasibility of using infrared thermography (IRT) to predict the internal temperature of the ETT.MethodsA new method for predicting the internal ETT temperature using an IRT camera was established, and its accuracy and reliability were evaluated under various conditions. The external surface temperature of the ETT was measured with IRT, and the internal temperature was measured with thin thermocouples, which has minimal effect on ventilation and served as a true value. Temperature measurements were taken at two points, distal and proximal, respectively, to capture temperature changes during passage of gases through the ETT.ResultsThis method allowed prediction of the internal ETT temperature with high accuracy (R2Adj = 0.946 and 0.974 at the proximal and distal ends, respectively). The internal and external temperatures of the ETT were related to the incubator temperature and ventilator mode. The effects of the size of the ETT, the set temperature of the constant‐temperature tank, and the heated humidifier temperature were limited.ConclusionThis non‐contact method of internal temperature prediction allows continuous monitoring without interfering with ventilation, and will help airway management in the neonatal intensive care unit.

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Oxygen With Cold Bubble Humidification Is No Better Than Dry Oxygen in Preventing Mucus Dehydration, Decreased Mucociliary Clearance, and Decline in Pulmonary Function

Cited by 21 publications

References 22 publications

Is humidified better than non‐humidified low‐flow oxygen therapy? A systematic review and meta‐analysis

Is humidified better than non‐humidified low‐flow oxygen therapy? A systematic review and meta‐analysis

Humidification therapy; long-term effects in COPD and OSAS patients

Internal Temperature of Neonatal Endotracheal Tube Predicted by Infrared Thermography: A Neonatal Bench Study

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