P-5 HEPATITIS E VIRUS INFECTION INCREASES THE RISK OF DIABETES AND MORTALITY IN HCV infected patients

Zitelli, Patricia Momoyo Yoshimura; Gomes‐Gouvêa, Michele Soares; Mazo, Daniel F.; Singer, Júlio da Motta; Oliveira, Conceição Maria de; Farias, Alberto Queiróz; Pinho, João Renato Rebello; YukimatsuTanigawa, Ryan; Alves, Venâncio Avancini Ferreira; Carrilho, Flair José

doi:10.1016/j.aohep.2021.100371

Cited by 2 publications

(2 citation statements)

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“…reported that chronic HEV infection might occur in HIV-infected patients and is associated with active hepatitis ( Dalton et al., 2009 ). There are also cases of HEV superinfection with hepatitis A, hepatitis B, hepatitis C, Campylobacter jejuni , Giardia intestinalis , or malaria, which indicates that HEV infection may exacerbate liver damage, accelerate disease progression, and increase mortality in patients with cirrhosis or chronic liver disease ( Lorenzo et al., 2016 ; Sahra et al., 2021 ; Butt et al., 2019 ; Tseng et al., 2020 ; Zitelli et al., 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Co-infection of hepatitis E virus, Clonorchis sinensis, and Escherichia coli: A case report

Zhang

Wang

Zhang

et al. 2023

Front. Cell. Infect. Microbiol.

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Hepatitis E virus (HEV) is a common cause of acute hepatitis that threatens human health worldwide. With the popularization of detection technology, the reports of hepatitis E have gradually increased. Here, we present a rare case of co-infection with hepatitis E viruses, Clonorchis sinensis and Escherichia coli. A 52-year-old man was hospitalized because of fatigue, jaundice, and nausea for more than 2 weeks. Laboratory tests showed elevated bilirubin, aminotransferase (ALT), and aspartate aminotransferase (AST); HEV-IgM was positive, and HEV-RNA could be detected. Moreover, parasites were found in the biliary drainage and the biliary culture, which suggested Escherichia coli. The patient was effectively treated with praziquantel, imipenem, and hepatoprotective drugs and his clinical symptoms were relieved after 2 months; total bilirubin decreased to 85.1 μmol/L, ALT decreased to 92.4 U/L, and AST decreased to 102 U/L.

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Section: Discussionmentioning

confidence: 99%

Co-infection of hepatitis E virus, Clonorchis sinensis, and Escherichia coli: A case report

Zhang

Wang

Zhang

et al. 2023

Front. Cell. Infect. Microbiol.

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“… 163 Brazilian authors found 12.0% (22/181) anti-HEV IgG seropositivity in individuals with chronic HCV. 164 In 2021, Wong et al reported 8.66% HEV IgG seroprevalence among adults with chronic HCV. 159 Korean scientists presented 33.3% anti-HEV IgG positivity prevalence in 502 patients with chronic HCV.…”

Section: Hev Among Individuals With Chronic Liver Diseasementioning

confidence: 99%

Hepatitis E Virus (HEV) Infection Among Immunocompromised Individuals: A Brief Narrative Review

Alexandrova,

Tsachev,

Kirov

et al. 2024

IDR

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Hepatitis E virus (HEV) is a single-stranded positive-sense RNA virus that belongs to Hepeviridae family. HEV is the most common cause of acute viral hepatitis worldwide. According to the World Health Organization (WHO), there are estimated 20 million HEV infections worldwide every year, leading to estimated 3.3 million symptomatic cases of HEV infection. The WHO estimates that HEV infection caused approximately 44,000 deaths in 2015, which represents 3.3% of mortality rates due to viral hepatitis. In low-income (LI) countries and lower-middle-income (LMI) countries, HEV is a waterborne infection induced by HEV genotype (gt) 1 and HEV gt 2 that cause large outbreaks and affect young individuals with a high mortality rate in pregnant women from South Asian countries and patients with liver diseases. HEV gt 3, HEV gt 4, and HEV gt 7 are responsible for sporadic infections with zoonotic transmission mainly through the consumption of raw or undercooked meat from different animals. Acute HEV infection is relatively asymptomatic or mild clinical form, in rare cases the disease can be moderate/severe clinical forms and result in fulminant hepatitis or acute liver failure (ALF). Furthermore, HEV infection is associated with extrahepatic manifestations, including renal and neurological clinical signs and symptoms. Pregnant women, infants, older people, immunocompromised individuals, patients with comorbidities, and workers who come into close contact with HEV-infected animals are recognized as major risk groups for severe clinical form of HEV infection and fatal outcome. Chronic HEV infection can occur in immunocompromised individuals with the possibility of progression to cirrhosis.

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P-5 HEPATITIS E VIRUS INFECTION INCREASES THE RISK OF DIABETES AND MORTALITY IN HCV infected patients

Cited by 2 publications

References 0 publications

Co-infection of hepatitis E virus, Clonorchis sinensis, and Escherichia coli: A case report

Co-infection of hepatitis E virus, Clonorchis sinensis, and Escherichia coli: A case report

Hepatitis E Virus (HEV) Infection Among Immunocompromised Individuals: A Brief Narrative Review

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