2022
DOI: 10.21203/rs.3.rs-1889286/v1
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P- element Induced Wimpy Testis (PIWI), a Novel Powerful Candidate Diagnostic Marker for Hepatocellular Carcinoma

Abstract: P-Element-induced wimpy testis (PIWI) proteins are engaged in epigenetic regulation of gene expression in germline cells when they are in combination with PIWI-interacting RNA (piRNA). Different types of tumour cells have been found to exhibit abnormal expression of piRNA and PIWI proteins. HCC is majorly diagnosed in later stages, which is associated with lower survival rates. There is an urgent need for improved, more specific and less invasive diagnostic methods that can detect earlier stages of the disease… Show more

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