P Wave Dispersion in Hypertensive Patients with Paroxysmal Atrial Fibrillation

Abstract

P Wave Dispersion in Hypertensive Patients with Paroxysmal Atrial Fibrillation. It is important to assess the risk of developing paroxysmal atrial fibrillation (PAF) in hypertensive patients since hypertension is a common disorder predisposing to PAF. We sought to determine if patients with hy pertension at risk of PAF can be identified while in sinus rhythm by measurements ofP wave dispersion. Twelve-lead surface electrocardiograms were recorded in 44 hypertensive patients with history of PAF (group I, mean age = 60) and in 50 hypertensive patients without history ofAF (group II, mean age = 57). The maximum P wave duration, the minimum P wave duration, and P wave dispersion (Pd = Pmax -Pmin) were calculated from 12-lead surface ECGs. Left atrial dimension (LAD) and left ventricular ejec tion fraction (LVEF) were measured by echocardiography. P wave dispersion was significantly greater in group I than group II (50 ± 12 vs 38 ± 8 ms, P = 0.001). P minimum (75 ± 13 vs 87 ± 11 ms, P = 0.001) and LVEF (0.63 ± 0.05 vs 0.67 ± 0.04, P = 0.03) were significantly lower in group I than group II. How ever P maximum and LAD were not significantly different in group I than group II (P > 0.05). In univariate analysis, P minimum, P wave dispersion, and LVEF were significant predictors of PAF, whereas only P wave dispersion remained a significant independent predictor of PAF in a multivariate analysis. Mea surement of P wave dispersion in sinus rhythm may be a useful noninvasive clinical tool to identify pa tients with hypertension at risk of developing atrial electrical instability and atrial fibrillation. (PACE 2000; 23[Pt. II]'-.1859-1862 hypertension, paroxysmal atrial fibrillation, P wave dispersionAddress for reprints: Necia Özer, M.D., ZiraatMah, 14.sok, 8/6,

Meta‐analysis of Vitamin D Deficiency and Risk of Atrial Fibrillation

“…Vitamin D has antioxidant properties that protect against oxidative stress in the atrium. 31 More recently, Canpolat et al 32 demonstrated that Pwave dispersion and atrial electromechanical delay, which are associated with increased risk for the development of AF, 33,34 were significantly prolonged in patients with vitamin D deficiency compared with controls (P < 0.001). Meanwhile, we have previously hypothesized that prolonged P-wave dispersion and atrial electromechanical delay may be due to electrical and structural remodeling of the atrium secondary to inflammation and oxidative stress.…”

Value of interatrial conduction time and P wave dispersion in prediction of atrial fibrillation following coronary bypass surgery

“…Bu tekniğin değişik hasta popülasyonlarında AF öngörücüsü olarak kullanılabilece-ğine ait birçok yayın vardır. Arteriyel hipertansiyonlu, DDD pacemaker'lı, hipertiroidili, hipertrofik kardiyomiyopatili, kronik böbrek yetmezlikli olgularda PDD artışının AF' yi öngörücü gücü-ne ait yayınlar vardır (9,(22)(23)(24)(25). P dalga dispersiyonundaki artışın KABC sonrası AF' yi öngörmek için kullanılabileceği daha önce rapor edilmiştir (26).…”

The effect of nebivolol on P wave duration and dispersion in patients with Behçet’s disease; a prospective single-arm controlled study

“…Accordingly, many investigators have searched the PD in many cardiac diseases to determine whether it is useful or not to predict the risk of AF. Based on the available data obtained from these investigations, PD may be considered as a noninvasive electrocardiographic marker to predict the risk of AF, especially in some cardiovascular disorders as cardiomyopathy, rheumatic mitral stenosis, ischemic heart disease, hypertension, and paroxysmal AF which characterized with a high prevalence of AF (7,8,(25)(26)(27)(28)(29)(30)(31).…”