P02.92: Routine fetal anomaly screening: a DGH experience

Abstract

Poster abstracts pregnancies including a detailed morphological scan, additionally the investigation of the four chamber view and the leftand right ventricular outflow tracts. From this group, in 585 singleton pregnancies second-trimester-screening at 18-22 weeks was performed. The perinatal outcome (mode of delivery, birth weight, Apgar score, umbilical cord pH and perinatal mortality) of 570 cases was recorded. Results: The median maternal age of the 603 cases was 31 (range, 16-44), the median gestation at first-trimesterscreening was 12 + 6 (11 + 1 to 13 + 6) weeks and the median gestation at second-trimester-screening was 19 + 2 (18 + 0 to 21 + 6). Nineteen (3%) of the 603 fetuses had a chromosomal abnormality. Of the 603 fetuses had twenty a termination of pregnancy, 6 a spontaneous abortion and 7 an intrauterine fetal death. 44 of the 603 fetuses had 88 structural abnormalities considered as being detectable by sonography. 6 fetuses of the 570 with perinatal outcome had a chromosomal abnormality (2x 47XXY and 4x other) and 21 fetuses had 31 structural abnormalities detected at first-and second-trimester-screening. However, parameters of initial neonatal adaptation did not differ significantly. Conclusion: First-trimester screening leads to an early identification and selection of pregnancies with adverse outcome. Fetuses with structural abnormities are regarding the early neonatal period and postnatal adaptation comparable to healthy newborns.