P152. A DGH’s experience using Magseed as a localisation tool for impalpable breast lesions

Crane, Jasmine; Photi, Evangelos; Down, Sue

doi:10.1016/j.ejso.2019.01.172

Cited by 3 publications

(4 citation statements)

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“…This difference might be partially attributed to the fact that centres reporting Magseed experience are more likely to be academic with a high volume of cases and have greater radiological and surgical expertise than others. However, we found no significant difference in the reexcision rates between Magseed and WGL in the separate pooled analysis of four suitable studies (12,13,22,30).…”

Section: Discussioncontrasting

confidence: 64%

“…We then proceeded to screen the full texts, when available, for the 21 abstracts which initially met the criteria for analysing Magseed localisation efficacy (9,(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30). Five studies were excluded from the localisation/identification rate calculation because these data was not provided or were unclear (12,15,21) or because the total number of Magseeds used was unclear (13,22). Hence, 16 studies were used to calculate the rates of successful localisation and placement in the pooled analysis (9,11,14,(16)(17)(18)(19)(20)(23)(24)(25)(26)(27)(28)(29)(30).…”

Section: Resultsmentioning

confidence: 99%

“…Four studies were included in a smaller pooled analysis which selectively examined the use of Magseeds in direct comparison to WGL (12,13,22,30). This analysis included some studies excluded from the larger pooled analysis because relevant data were found directly comparing the two methods.…”

Section: Resultsmentioning

confidence: 99%

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Evolving Role of Magseed in Wireless Localization of Breast Lesions: Systematic Review and Pooled Analysis of 1,559 Procedures

Gera

Tayeh

Al-Reefy³

et al. 2020

Anticancer Res

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Background/Aim: Wire-guided localisation (WGL) remains the most widely used technique for the localisation of non-palpable breast lesions; however, recent technological advances have resulted in non-wire, non-radioactive alternatives, such as magnetic seeds (Magseeds). The aim of this pooled analysis was to determine whether Magseeds are an effective tool for localising non-palpable breast lesions. Materials and Methods: Various databases were searched for publications which reported data on the localisation and placement rates of Magseed. Data on re-excision rates under use of Magseed and WGL were also collected. Results: Sixteen studies, spanning the insertion of 1,559 Magseeds, were analysed. The pooled analysis showed a successful placement rate of 94.42% and a successful localisation rate of 99.86%. Four studies were analysed in a separate pooled analysis and showed no statistically significant difference between reexcision rates using Magseeds and WGL. Conclusion: The use of Magseeds is an effective, non-inferior alternative to WGL that overcomes many of the limitations of the latter. The pre-operative localisation of non-palpable breast cancer traditionally employs wire-guided localisation (WGL) (1). However, several limitations are associated with WGL. The localisation wire can cause manifold complications, such as diathermy burns, pericardial injury and wire dislocation/ transection (2, 3). Furthermore, wire migration and surgical difficulties in accurately assessing the position of the wire tip intraoperatively can pose significant difficulty for the operating surgeon (4). WGL is performed on the day of surgery, and interdepartmental coordination with radiology for localisation in addition to everyday scheduling difficulties may lead to a prolonged surgical waiting time. An underreported limitation of the flexible wire used in WGL is that it increases the risk of needle-stick injury for the surgeon and the pathologist. Furthermore, it protrudes from the breast and is uncomfortable for the patient. The prospect of an additional procedure on the day of major breast surgery can also be very stressful for patients in whom anxiety level is already high (2). Widespread use of screening methods has led to an increased incidence of non-palpable breast cancer. It is therefore imperative that localisation methods with high patient, radiologist and surgical satisfaction rates are developed. Radioactive seed localisation (RSL) is a feasible alternative to WGL. RSL can occur up to 5 days prior to the surgery and the seeds can be accurately detected with a hand-held gamma probe (5). Furthermore, recent evidence suggests that RSL would be more cost-effective than WGL (6) and would improve the oncological outcomes of imageguided surgery (7). However, handling of radioactive material requires special licensing and is associated with strict regulatory requirements. Hence, the optimal solution would be a non-wire non-radioactive localisation method which contains no energy source. This has led to the emergence of Savi Sco...

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Section: Discussioncontrasting

confidence: 64%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Evolving Role of Magseed in Wireless Localization of Breast Lesions: Systematic Review and Pooled Analysis of 1,559 Procedures

Gera

Tayeh

Al-Reefy³

et al. 2020

Anticancer Res

View full text Add to dashboard Cite

show abstract

“…To date, few studies have been conducted for a direct comparison of surgical outcomes between Magseed localisation and HWL. Those performed in European populations observed comparable rates of margin positivity and re-excision, 23,24 but no data are available in Asia. Previously, Walsh et al 25 concluded that higher breast density is associated with higher re-excision rates in women having breast-conserving surgery.…”

Section: (A) (B) (C)mentioning

confidence: 94%

Image-guided Localisation of Nonpalpable Breast Lesions: a Comparative Analysis of Magnetic Seeds and Hookwires in an Asian Population

Yang

Wong

Leong

et al. 2022

Hong Kong Journal of Radiology

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Objectives: To compare the procedural outcomes of magnetic seed localisation and hookwire localisation (HWL) of nonpalpable breast lesions in an Asian population. Methods: We performed a retrospective review of 91 nonrandomised female patients who underwent breast surgery after image-guided magnetic seed localisation or HWL from July 2019 to June 2021. Rates of placement success (defined as marker-lesion distance <10 mm), lesion detection, marker retrieval, and complications, were compared. Results: A total of 48 patients received magnetic seeds, and 43 patients received hookwires for preoperative localisation; a total of 100 lesions (50/100, 50.0% Magseed vs. 50/100, 50.0% hookwire) were marked and excised. Magnetic seeds were placed 0 to 126 days before surgery (median=14); of the 50 lesions marked, 22 were removed on the same day and 28 on a later day. Placement success was identical between the two groups, 98.0% magnetic seeds versus 98.0% hookwire. All lesions were detected at the first operation and successfully excised; all markers were removed intact without complications. Conclusion: Magnetic seed localisation demonstrated comparable procedural success and safety to conventional HWL in Asian patients with thinner and denser breasts. It could be an effective alternative to HWL, with the additional advantage of decoupling localisation and surgery dates.

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Wireless localisation of breast lesions with MagSeed. A radiological perspective of 300 cases

Constantinidis

Sakellariou

Chang

et al. 2022

BJR

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Objectives: The purpose of this article is to review the technical and radiological aspects of MagSeed® localisation, to assess its accuracy based on post-localisation mammograms and excision specimen X-rays and to discuss the radiological experience of our institutions. Methods: Two-year data were collected retrospectively from three NHS boards from the West of Scotland. A total of 309 MagSeeds® were inserted under mammographic or ultrasonographic guidance in 300 women with unifocal, multifocal and/or bilateral breast lesions at the day of surgery or up to 30 days prior to it. Radiological review of post-localisation mammograms and intraoperative specimen X-rays as well as a review of the surgical outcomes were performed to assess the accuracy and efficacy of the method. Our experience relating to the technique’s strengths and downsides were also noted. Results: The MagSeeds® were inserted on average 7.2 days before surgery. The localisation technique was straight forward for the radiologists. In 99% of the cases, the MagSeed® was successfully deployed and 100% of the successfully localised lesions were excised at surgery. There was no difference in the accuracy of the localisation whether this was mammographically or ultrasonographically guided. On post-localisation mammograms, the MagSeed® was radiologically accurately positioned in 97.3% of the cases. No delayed MagSeed® migration was observed. On the specimen X-rays, the lesion was centrally positioned in 45.1%, eccentric within more than 1 mm from the margin in 35.7% and in 14.8% it was at the specimen’s margin. The re-excision rate was 18.3%. Conclusion: The MagSeed® is an accurate and reliable localisation method in breast conserving surgery with good surgical outcomes. Advances in knowledge: To our knowledge, the radiological aspects of MagSeed® localisation have not been widely described in peer-reviewed journals thus far.

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P152. A DGH’s experience using Magseed as a localisation tool for impalpable breast lesions

Cited by 3 publications

References 0 publications

Evolving Role of Magseed in Wireless Localization of Breast Lesions: Systematic Review and Pooled Analysis of 1,559 Procedures

Evolving Role of Magseed in Wireless Localization of Breast Lesions: Systematic Review and Pooled Analysis of 1,559 Procedures

Image-guided Localisation of Nonpalpable Breast Lesions: a Comparative Analysis of Magnetic Seeds and Hookwires in an Asian Population

Wireless localisation of breast lesions with MagSeed. A radiological perspective of 300 cases

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