P2-243: A Phase II study of Carboplatin plus Pemetrexed in previously treated patients with non-small cell lung cancer (NSCLC)

Abstract

Objective: To study the effects of Taxotere, Celecoxib and the combination of both on proliferation and apoptosis of NSCLC cell. Methods: Investigate the effect of Taxotere, Celecoxib and the combination of both on proliferation of NSCLC A549 by MTT assays. Detect the change of apoptosis, cell cycle and the expression of COX-2 protein using flow cytometry analysis and immunocytochemistry, respectively.