P62 Poly-autoimmunity frequency in SLE patients from a tertiary hospital

Abstract

transglutaminase (IgA) antibodies. Six patients were DQ2 positive. After being diagnosed of CD and starting the GFD, SLE patients seem to improve especially the leukopenia, lymphopenia and oral aphtosis, as well as SLEDAI score (showed in attached graphics). Conclusions SLE patients with CD diagnosis and who started a GFD, showed improvement of leukopenia, lymphopenia, oral aphtosis and even SLEDAI. In SLE patients with recurrent oral aphtosis and/or gastrointestinal unspecific symptoms, CD should be considered, but since serological screening displays a low sensitivity, HLA testing could be helpful. Gastroscopy should be considered, with biopsy and flow cytometer in uncertain cases. Even though, further studies, especially looking for different clinical profiles and longer observational period are needed.