Pacemaker-induced cardiomyopathy

Fletcher-Hall, Shirley

doi:10.1097/01.jaa.0000947080.85880.bb

Cited by 2 publications

(1 citation statement)

References 21 publications

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“…Whereas, concerns have arisen with the increasing evidence on RVP. Accumulated studies suggest that RVP is significantly associated with the ventricular electromechanical dyssynchrony, ultimately causing to increased atrial arrhythmias, heart failure, and mortality[3, 4]. Therefore, establishment of an alternative pacing strategy for decreasing the risk of new-onset AF after pacing therapy is necessary.…”

Section: Introductionmentioning

confidence: 99%

Conduction system pacing is superior to reduce the new-onset atrial fibrillation risk compared with right ventricular pacing: insights from pooled clinical evidence

Li,

Zhang,

Peng

et al. 2024

Preprint

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BackgroundConduction system pacing (CSP) has been reported to improve clinical outcomes in comparison of right ventricular pacing (RVP). However, the performance between CSP and RVP on the risk of new-onset atrial fibrillation (AF) remains elusive.MethodsFour online databases were systematically searched up to December 1st2023. Studies comprising the rate/risk of new-onset AF between CSP and RVP group were included. Subgroup analysis was performed to screen the potential determinants for the new-onset AF risk for CSP therapy. Moreover, the pooled risk of new-onset AF based on ventricular pacing burden (Vp) between CSP and RVP group were evaluated.ResultsA total of five studies including 1,491 patients requiring pacing therapy were eligible. The pooled new-onset AF rates for CSP and RVP group were 0.09 and 0.26, respectively. Compared with RVP group, CSP group showed a lower pooled risk (risk ratio [RR] 0.38,P=0.000) and adjusted risk (hazard ratio [HR] 0.33,P=0.000) of new-onset AF. Meanwhile, a significant intervention-covariate interaction for the adjusted risk of new-onset AF between CSP and RVP group was identified with Vp < 20% and Vp ≥ 20%.ConclusionsOur study suggests that CSP is superior to reduce the new-onset atrial fibrillation risk compared with RVP. The Vp ≥ 20% may be the key determinant on the lower risk of new-onset AF with CSP therapy.

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Section: Introductionmentioning

confidence: 99%

Conduction system pacing is superior to reduce the new-onset atrial fibrillation risk compared with right ventricular pacing: insights from pooled clinical evidence

Li,

Zhang,

Peng

et al. 2024

Preprint

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Dual-chamber pacing confers better myocardial performance and improves clinical outcomes compared to single-chamber pacing

Mohan,

Batta

2024

World J Cardiol

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The deleterious effects of long term right ventricular pacing are increasingly being recognized today. Current clinical practice favors the implantation of dual-chamber permanent pacemaker which maintains atrioventricular synchrony and is associated with better quality of life. However, despite the popular belief and common sense surrounding the superiority of dual-chamber pacing over single chamber pacing, the same has never been conclusively verified in clinical trials. Some observational evidence however, does exists which supports the improved cardiac hemodynamics, lower the rate of atrial fibrillation, heart failure and stroke in dual-chamber pacing compared to single-chamber pacing. In the index study by Haque et al , right ventricular pacing, particularly in ventricular paced, ventricular sensed, inhibited response and rate responsive pacemaker adversely impacted the left ventricular functions over 9-months compared to dual pacing, dual sensing, dual responsive and rate responsive pacemaker. Although there are key limitations of this study, these findings does support a growing body of evidence reinstating the superiority of dual chamber pacing compared to single chamber pacing.

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Pacemaker-induced cardiomyopathy

Cited by 2 publications

References 21 publications

Conduction system pacing is superior to reduce the new-onset atrial fibrillation risk compared with right ventricular pacing: insights from pooled clinical evidence

Conduction system pacing is superior to reduce the new-onset atrial fibrillation risk compared with right ventricular pacing: insights from pooled clinical evidence

Dual-chamber pacing confers better myocardial performance and improves clinical outcomes compared to single-chamber pacing

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