Painful and Pruritic Blisters on the Lower Lip

Abstract

A 41-year-old woman presented with a 2-day history of burning, stinging, itchy blisters on the lower lip. She had experienced a similar eruption at the same site with spontaneous resolution 1 year previously, after she had taken a cold medication containing ibuprofen. Her medical history was otherwise unremarkable. She took no prescription medications; however, she did occasionally take over-the-counter ibuprofen. On examination, she was wellappearing and afebrile. There were tense confluent blisters in a 4-cm area on and around the lower lip (Figure 1) and no other skin or mucosal lesions. Diagnosis Bullous nonpigmenting fixed drug eruption What to Do Next C. Discontinue ibuprofen