Org. Chem. Front.
 2025
DOI: 10.1039/d4qo02024c
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Palladium-catalyzed dearomative Heck/[4 + 3] decarboxylative cyclization of indoles with α-oxocarboxylic acids via C–H activation

Liwei Zhou,
Pengyang Jing,
Wenbo Deng
et al.

Abstract: Herein, we report a novel palladium-catalyzed dearomative Heck/[4 + 3] decarboxylative cyclization of C2-tethered indoles with α-oxocarboxylic acids via C−H activation. In this reaction, dearomatization of C2-tethered indoles occurs via...

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