Palladium Nanoparticles Synthesized by Laser Ablation in Liquids for Antimicrobial Applications

Abstract

Antibiotic resistance is a leading cause of death worldwide. In this paper, we explore new alternatives in the treatment of infections. Noble metal nanoparticles could help to mitigate this problem. In this work, palladium nanoparticles were synthesized by laser ablation in order to explore their antimicrobial capacity. To obtain palladium nanoparticles, a palladium plate immersed in water, or methanol, was ablated, using two pulsed lasers that emit radiation with wavelengths of 532 nm and 1064 nm, respectively. Pure Pd-NPs with crystalline microstructure and rounded shape were obtained. The nanoparticles’ size is more homogeneous if the laser wavelength is 532 nm, and it decreases when methanol is used as solvent, reaching mean diameters smaller than 6 nm. With the objective of studying antimicrobial activity against Staphylococcus aureus, the Pd-NPs were immobilized on the surface of titanium discs. The release of palladium ions was recorded during the first seven days, and the cytotoxicity of the immobilized NPs was also tested with L929 mouse fibroblast cell line. Palladium nanoparticles synthesized by means of the infrared laser in methanol showed a strong inhibitory effect on S. aureus and good cytocompatibility, with no toxic effect on fibroblast cells.

Laser-assisted synthesis of metallic composite nanostructures in aqueous solutions

“…Composite nanostructures of noble metal or bimetals of (Au, Ag, Pt or Pd) and titania or zinc oxide are of great interest because of the plasmon-induced enhancement of their photovoltaic efficiency and photocatalytic activity [8][9][10], for biomedicine and sensing applications [11,12], etc.…”

AIEgen orthopalladated hybrid polymers for efficient inactivation of the total coliforms in urban wastewater

“…Organopalladium tools are good inactivators of the world's best-characterized, ubiquitous, and adaptable organism, Escherichia coli [39,40]. Escherichia coli is the most representative microbial species of the faecal coliform group, in turn, part of the larger family of total coliforms, present in the digestive tracts of animals, in wastes, in plants, and in soil material.…”

AIEgen orthopalladated hybrid polymers for efficient inactivation of the total coliforms in urban wastewater

“…Palladium organometallic complexes are widely employed in bioinorganic chemistry 40 , 41 . Organopalladium tools are good inactivators of the world’s best-characterized, ubiquitous, and adaptable organism, Escherichia coli 42 , 43 . Escherichia coli is the most representative microbial species of the faecal coliform group, in turn, part of the larger family of total coliforms, present in the digestive tracts of animals, in wastes, in plants, and in soil material.…”