Palm stearin and olein binary mixture incorporated into nanostructured lipids carrier: Improvement food functionality for micronutrient delivery

Rohmah, Miftakhur; Choiri, Syaiful; Raharjo, Sri; Hidayat, Chusnul; Martien, Ronny

doi:10.1111/jfpp.14761

Cited by 3 publications

(10 citation statements)

References 32 publications

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“…Delivery system based on PO and PS is an effort to utilize local raw materials to increase bioaccessibility of the bioactive substance such as βC in the digestive system. In previous studies, this delivery system has been tested for its physical stability and chemical properties (Rohmah et al, 2020a;Rohmah et al, 2020b). However, how much of the active component of βC is available in a delivery system needs to be known in a simulated in vitro digestive model.…”

Section: In Vitro Release Of βC From the βC-nlcmentioning

confidence: 99%

“…However, the reports on the application of lipids derived from palm oil fractionation of palm stearin (PS) as solid lipid and palm olein (PO) as liquid lipid is still very limited. In the light of the previous studies ( Rohmah, 2020a , 2020b ), PS and PO with Tween 80 surfactant can be used to deliver micronutrients via the NLC system. While the fatty acids compositions of PS and PO were similar, their respective proportion influenced their physicochemical properties and crystallinity.…”

Section: Introductionmentioning

confidence: 98%

“…The NLC has high encapsulation and controlled release abilities. It is thermodynamically stable, while bioactive components bioavailability is observed ( Tamjidi et al., 2013 ; Rohmah et al., 2020a ; Rohmah et al., 2020b ; Elmowafy and Al-Sanea, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

“…The Differential Scanning Calorimetry-Thermal Gravimetry analysis demonstrates that βC-NLC has a high thermal stability. According to the Franz diffusion model, the optimized βC-NLC exhibits favorable diffusion properties ( Rohmah, 2020b ). However, the biological activity of this delivery system is yet to be reported.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Bioaccessibility and antioxidant activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm olein

Rohmah

Rahmadi

Raharjo

2022

Heliyon

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activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm olein, HELIYON, https://doi.org/10.1016/j.heliyon.2022.e08913. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: In Vitro Release Of βC From the βC-nlcmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Bioaccessibility and antioxidant activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm olein

Rohmah

Rahmadi

Raharjo

2022

Heliyon

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“…Despite the emerging success of mass spectrometry (as an important tool in lipidomics) [ 5 , 6 , 7 , 8 , 9 , 10 ], traditional chromatographic techniques remain widely used for food lipid analysis [ 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. Normal-phase high-performance liquid chromatography (HPLC) coupled to evaporative light scattering detection (ELSD) is particularly useful for separating lipids into individual classes according to the number and type of polar functional groups and has successfully been used to study the lipid composition of samples of various origin [ 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Normal-Phase HPLC-ELSD to Compare Lipid Profiles of Different Wheat Flours

Melis

Foubert

Delcour

2021

Foods

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Normal-phase high-performance liquid chromatography (HPLC) is widely used in combination with evaporative light scattering detection (ELSD) for separating and detecting lipids in various food samples. ELSD responses of different lipids were evaluated to elucidate the possibilities and challenges associated with quantification by means of HPLC-ELSD. Not only the number and type of polar functional groups but also the chain length and degree of unsaturation of (free or esterified) fatty acids (FAs) had a significant effect on ELSD responses. Tripalmitin and trilinolein yielded notably different ELSD responses, even if their constituting free FAs produced identical responses. How FA structure impacts ELSD responses of free FAs is thus not predictive for those of triacylglycerols and presumably other lipids containing esterified FAs. Because ELSD responses of lipids depend on the identity of the (esterified) FA(s) which they contain, fully accurate lipid quantification with HPLC-ELSD is challenging and time-consuming. Nonetheless, HPLC-ELSD is a good and fast technique to semi-quantitatively compare the levels of different lipid classes between samples of comparable FA composition. In this way, lipid profiles of different flours from near-isogenic wheat lines could be compared.

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Formulation and Characteristics of Nanostuctured Lipid Carrier (NLC) Red Palm Oil (RPO) Prepared by High-Pressure Homogenization and Its Applications in Orange Juice

Wirawan,

Raharjo,

Supriyadi

2023

IFNP

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A Nanostructured lipid carrier (NLC) is an emulsion system that can encapsulate and improve stability of lipid-based bioactive compounds. This study aimed to develop an optimal RPO-NLC formula with a combination of solid and liquid lipids, lipids and surfactants, and the use of high-pressure homogenizer (HPH). RPO-NLC was made using HPH with a 400 bar and 600 bar pressure. A Completely randomized design (CRD) with three factors was used to determine interactions between factors. The RPO-NLC formula was characterized based on particle size. One of the best formulas was selected with small particle size and high RPO content then characterized based on encapsulation efficiency (EE), loading capacity (LC), storage stability, FTIR, thermal and applied to orange juice including sensory evaluation, encapsulation stability and pH. RPO-NLC yielded particle size 44.9 nm, EE 99.9±0.02%, LC 4.9±0.001%, was stable on storage. β-carotene identified in RPO-NLC lipid matrix based on FTIR analysis and has good thermal stability based on differential scanning calorimeter analysis. Sensory evaluation showed changes in sensory attributes of color, aroma, taste during storage. Encapsulation stability showed significant increase during storage and pH measurement results also increased.

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Palm stearin and olein binary mixture incorporated into nanostructured lipids carrier: Improvement food functionality for micronutrient delivery

Abstract: Recent years, nanotechnology is still developing in a food science field particularly as a delivery system of micro/macronutrients to enhance food quality. In addition, it can be implemented to be developed as a functional food (Huang,

Cited by 3 publications

References 32 publications

Bioaccessibility and antioxidant activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm olein

Bioaccessibility and antioxidant activity of β-carotene loaded nanostructured lipid carrier (NLC) from binary mixtures of palm stearin and palm olein

Normal-Phase HPLC-ELSD to Compare Lipid Profiles of Different Wheat Flours

Formulation and Characteristics of Nanostuctured Lipid Carrier (NLC) Red Palm Oil (RPO) Prepared by High-Pressure Homogenization and Its Applications in Orange Juice

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