Palpitations across the menopause transition in SWAN: trajectories, characteristics, and associations with subclinical cardiovascular disease

Carpenter, Janet S.; Cortés, Yamnia I.; Tisdale, James E.; Sheng, Ying; Jackson, Elizabeth A.; Barinas‐Mitchell, Emma; Thurston, Rebecca C.

doi:10.1097/gme.0000000000002082

Cited by 4 publications

(5 citation statements)

References 57 publications

(116 reference statements)

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“…Although studies have attempted to identify precipitating factors or antecedents of palpitations in peri-and postmenopausal women, 4 little research has examined their long term impact. 2 The third finding was the variability in healthcare experiences described by the women. Current clinical practice recommendations for palpitations are to obtain medical history, perform physical examination, and obtain a 12-lead ECG while patients are symptomatic.…”

Section: Discussionmentioning

confidence: 98%

“…If different subtypes emerged in a larger study, it might be possible to further identify their precipitating factors or antecedents (eg, demographics, gynecological history, menopause status) as well as their impact on health outcomes (eg, cardiovascular events). Although studies have attempted to identify precipitating factors or antecedents of palpitations in peri- and postmenopausal women, 4 little research has examined their long term impact 2 …”

Section: Discussionmentioning

confidence: 99%

“…Palpitations are more common in women than in men and are associated with negative health outcomes 1 . Women may experience palpitations during peri- and postmenopause, 2 along with vasomotor and other menopausal symptoms. Although much has been written about menopausal vasomotor symptoms, less has been written about menopausal palpitations.…”

mentioning

confidence: 99%

“…immediately before, during, or immediately after palpitations;[2] frequent dilute urination;[3] other concurrent symptoms of fatigue, sleep disturbances, anxiety, depression, pain [neck, chest, headaches].) Aggravating and alleviating factors Sometimes people notice things that make their palpitations better or worse.…”

mentioning

confidence: 99%

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“Quick flutter skip”: midlife women's descriptions of palpitations

Carpenter,

Fagan,

Alzahrani

et al. 2023

Menopause

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Objective The objective of this study is to describe peri- and postmenopausal women's experiences of palpitations (quality, frequency, severity, distress, duration and temporal pattern, aura, associated symptoms, and aggravating/alleviating factors) and related healthcare experiences. Methods Qualitative descriptive methods were used. Semistructured interviews were conducted with women who reported palpitations and were enrolled in a larger case-control pilot study comparing electrocardiographic results between women with and without palpitations. Authors analyzed women's narratives using standard content analytic procedures. Results Fourteen participants (mean age, 54.5 y [SD = 4.8 y]; range, 46-62 y; 79% postmenopausal) completed interviews. The interviews revealed that women (a) often had difficulty describing their palpitations until prompted by the interviewer; (b) experienced noteworthy variations in the quality and other dimensions of their palpitations; (c) had a wide variety of healthcare experiences related to their palpitations, including not reporting their symptoms to providers, having providers dismiss their symptoms, and having providers be aware of their symptoms and provide diagnostic tests; and (d) at times, created worst case scenarios (downward shifts) under which they would seek treatment for their palpitations, thus enabling them to minimize their symptoms and avoid healthcare. Conclusion This study advances understanding of how women describe their palpitations and related healthcare experiences. Findings could have implications for building research and clinical tools to guide assessment, communication, and/or education for patients and/or providers about palpitations and for developing and testing behavioral interventions to address this poorly understood symptom in peri- and postmenopausal women.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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“Quick flutter skip”: midlife women's descriptions of palpitations

Carpenter,

Fagan,

Alzahrani

et al. 2023

Menopause

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“…The Study of Women Across the Nation (SWAN) is a community population-based study about women in the United States and their midlife physiologic hormonal transition to much lower serum levels of 17beta estradiol [34]. It is a multi-site, prospective, longitudinal, observational, cohort study of biological and psychosocial changes in a racially and ethnically diverse in the United States.…”

Section: Utilizing Advanced Technologiesmentioning

confidence: 99%

Primary Ovarian Insufficiency: A Case of the Cart before the Horse

Hijane,

Nelson

2024

Adv Med Res

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Overt Primary Ovarian Insufficiency (POI) is a rare disorder characterized by a constellation of other rare conditions, posing significant diagnostic and management challenges. This disorder necessitates a global mechanism for information exchange, streamlined data sharing, dynamic international partnerships, and the integration of artificial intelligence to enhance diagnostic accuracy through next-generation sequencing and specific antibody testing. Empowering women with POI involves providing them with access to the best available evidence at the point of care and facilitating informed decisions throughout their health journey. A key strategy is transcending the traditional biomedical model by adopting a population-based approach that encourages global cross-sectional collaboration. Optimal care for women with POI is achieved through an integrated, multidisciplinary approach that leverages diverse expertise to evaluate evidence and update care practices effectively. Initiatives are also underway to establish a patient advocacy group, emphasizing the importance of early diagnosis in allowing women to adapt family planning or preserve fertility. The overarching vision for POI research and care aims to cultivate proactive international partnerships and data sharing, driven by the needs and experiences of women with Overt POI.

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