Pancreatic Function in Hypothermia

Véghelyi, P; Kemeny, T; Zsinka, Agnes T.; Faur, N

doi:10.1038/200478a0

Cited by 8 publications

(3 citation statements)

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“…According to Veghelyi (1947Veghelyi ( ,1948 and Gomez, Ramos-Galvan, Cravioto & Frenk (1954), protein deficiency in children caused a dissociation in the secretion of the different enzymes similar to that observed by Veghelyi & Kemeny (1962). Conversely, Thompson & Trove11 (1952) recorded parallel variations in concentrations of amylase, lipase, and chymotrypsin in the intestinal lumen in children with kwashiorkor.…”

Section: Discussionmentioning

confidence: 87%

“…This sequence is probably dependent on the limiting amino acid. Veghelyi & Kemeny (1962) studied methionine deficiency while Christophe (1966), working with lysine deficiency, recorded the most intense reduction in the secretion of amylase.…”

Section: Discussionmentioning

confidence: 99%

“…According to Veghelyi & Kemeny (1962), the sequence of enzyme reduction in experimental protein deficiency was : lipase, trypsin and amylase. This sequence is probably dependent on the limiting amino acid.…”

Section: Discussionmentioning

confidence: 99%

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pH and Concentration of Pancreatic Enzymes in Aspirates from the Human Duodenum During Digestion of a Standard Meal in Patients with Intestinal Disorders

Worning¹,

Müllertz²,

Thaysen³

et al. 1967

Scandinavian Journal of Gastroenterology

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The material comprises 25 patients with gluten-induced enteropathy and 16 patients with various intestinal disorders. The intestinal contents were aspirated in four subsequent periods of 20 minutes each after ingestion of a standard meal. The volume, pH, and the concentration of alpha-amylase, trypsin, chymotrypsin, and lipase were determined in the collections. Only minor deviations from normal pH-levels were observed. In both groups of patients, the secretion of lipase, and to a minor degree that of amylase, were more markedly reduced than the secretion of the proteolytic enzymes. With the exception of the values of trypsin, concentrations of enzymes were seen to be below the lowest normal value in approximately one-third of the patients throughout the period of digestion. It is concluded that the pancreatic function was genuinely reduced in several patients with enterogenous malabsorption. It may be explained as an unspecific effect of the malabsorption.

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%