Pancreatography

Doubilet, Henry; Poppel, Maxwell H.; Mulholland, John H.

doi:10.1148/64.3.325

Cited by 76 publications

(7 citation statements)

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“…According to clinical and experimental studies of pancreatography (22,24,66,88,89), it became clear that the type, pressure, and volume of the injected contrast material were responsible for the complications of pancreatography. Since the report of Elmslie et al (24), Hypaque has been widely in use (33,45,50).…”

Section: Methodsmentioning

confidence: 99%

“…Let us recall that Doubilet et al (22) and Pollock (66) thought that acinar opacification due to extravasation of contrast material into the parenchyma of the pancreas was a characteristic finding of acute pancreatitis.…”

Section: Acute Pancreatitismentioning

confidence: 99%

“…The type of the opaque medium as well as the quantity of the solution may be fairly important, because some contrast materials (22), such as Diodrast and Urokon, activate trypsinogen in the pancreatic juice, possibly causing acute dam age to the pancreatic tissues. On the other hand, 50% Hypaque (sodium and diatrizoate), which is thought to be neither a chemical irritant to the pancreatic duct epithelium nor an activator of trypsinogen (24), has been widely used (24,45,50,88,89), as well as 60 % Urografin (sodium and methylglucamine diatri zoate) (59,(60)(61)(62)84), and 60 % Renografin (87), Conray 280 (meglumine iothalamete) (14) is also satisfactory, and no serious side effects have been reported.…”

Section: Contrast Materialsmentioning

confidence: 99%

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Recent Advances in the Endoscopic Retrograde Cholangiopancreatography

Kasugai

1975

Digestion

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Endoscopic retrograde cholangiopancreatography can become a safe and easy procedure by means of sterilization of the instruments. Administration of antibiotics or chemotherapeutic agents, both systemically and mixed with the contrast material, and measurement and control of the injection pressure of the contrast medium using a manometer are employed to achieve as aseptic an operation as possible. For diagnosis of pancreatic cancer in its early stage, as well as diagnosis of minimal and moderate chronic pancreatitis, opacification should extend into not only the main pancreatic duct, but also branches of the pancreatic duct and fine pancreatic ducts. The procedure is one of the most reliable methods for the detection of diseases of pancreatic and biliary systems, especially for the diagnosis of space-occupying lesions such as malignant tumors, and chronic inflammatory changes of the pancreas, as well as differential diagnosis in jaundiced patients.

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Section: Methodsmentioning

confidence: 99%

Section: Acute Pancreatitismentioning

confidence: 99%

Section: Contrast Materialsmentioning

confidence: 99%

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Recent Advances in the Endoscopic Retrograde Cholangiopancreatography

Kasugai

1975

Digestion

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“…7 This method was subsequently used by many American and European authors. A safe endoscopic method of performing pancreatography on a routine basis was sought for some years.…”

mentioning

confidence: 99%

Operative and endoscopic pancreatography in the diagnosis of pancreatic cancer

White

Silverstein

1976

Cancer

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X-rays of the pancreatic duct can now be obtained by a nonoperative endoscopic approach (endoscopic retrograde cholangiopancreatography-ERCP). After more than 2 years experience we have found that the pancreatic duct can be visualized in 85 to 90% of patients. This test is used to detect pancreatic carcinoma in the symptomatic patient and in searching for an operative pancreatic lesion in a patient with known recurrent or chronic pancreatitis. Many of these patients have pain or a transiently elevated amylase; a few have steatorrhea or abnormalities of the duodenal sweep on barium meal. Stenosis or obstruction of the main pancreatic duct with or without proximal duct dilation are the characteristic abnormalities noted in pancreatic carcinoma. A rare pancreatic tumor which is not in juxtaposition with the duct will have a normal pancreatogram although the common duct may be obstructed by cholangiography as it passes through the head of the pancreas. In patients with chronic pancreatitis it may be difficult to differentiate an inflammatory from a neoplastic stricture by either operative or endoscopic pancreatography. In the future, cytologic and biochemical examination of the pancreatic secretions obtained at ERCP may increase the accuracy of diagnosing carcinoma.

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“…pseudocyst formation due to leakage of pancreatic juice into the retroperitoneal space through one or more ducts involved in the necrosis, (2) …”

mentioning

confidence: 99%