“…DPMC generally begins before the age of 14 years, typically presenting with sclerotic plaques on the trunk and extensor areas progressing to the entire skin surface, eventually affecting muscle and bone . Walking becomes impossible because of contractures and mutilation caused by sclerosis, and patients often have joint contractures, calcinosis cutis, and nonhealing ulcers . The prognosis is poor, with severe orthopedic, psychological, and cosmetic disturbances, and the condition is often refractory to any treatment .…”