Paper-based microfluidic devices: Fabrication, detection, and significant applications in various fields

Das, Shibam; Gagandeep, .; Bhatia, Rohit

doi:10.1515/revac-2022-0037

Cited by 32 publications

(20 citation statements)

References 119 publications

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“…In fact, laser printing can be considered an updated version of wax printing for modern times [ 39 ]. They are a new generation of wax printers, using ink cartridges instead of wax cartridges in the printer [ 40 ]. Printing directly collects hydrophobic ink automatically, eliminating the need for human intervention.…”

Section: Design and Working Principles Of μPadsmentioning

confidence: 99%

Biomarker Detection in Early Diagnosis of Cancer: Recent Achievements in Point-of-Care Devices Based on Paper Microfluidics

et al. 2023

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Microfluidics is very crucial in lab-on-a-chip systems for carrying out operations in a large-scale laboratory environment on a single chip. Microfluidic systems are miniaturized devices in which the fluid behavior and control can be manipulated on a small platform, with surface forces on the platform being greater than volumetric forces depending on the test method used. In recent years, paper-based microfluidic analytical devices (μPADs) have been developed to be used in point-of-care (POC) technologies. μPADs have numerous advantages, including ease of use, low cost, capillary action liquid transfer without the need for power, the ability to store reagents in active form in the fiber network, and the capability to perform multiple tests using various measurement techniques. These benefits are critical in the advancement of paper-based microfluidics in the fields of disease diagnosis, drug application, and environment and food safety. Cancer is one of the most critical diseases for early detection all around the world. Detecting cancer-specific biomarkers provides significant data for both early diagnosis and controlling the disease progression. μPADs for cancer biomarker detection hold great promise for improving cure rates, quality of life, and minimizing treatment costs. Although various types of bioanalytical platforms are available for the detection of cancer biomarkers, there are limited studies and critical reviews on paper-based microfluidic platforms in the literature. Hence, this article aims to draw attention to these gaps in the literature as well as the features that future platforms should have.

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Section: Design and Working Principles Of μPadsmentioning

confidence: 99%

Biomarker Detection in Early Diagnosis of Cancer: Recent Achievements in Point-of-Care Devices Based on Paper Microfluidics

et al. 2023

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“…Paper has the structure of a microporous capillary network allowing solvent flow [81]. Its high porosity is expected to reduce the drag between the analyte and fiber, thereby minimizing waste during capillary fluid transport [25].…”

Section: Microfluidic Fabrication Materialsmentioning

confidence: 99%

Research progress on pesticide residue detection based on microfluidic technology

Zhu

et al. 2023

Electrophoresis

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The problem of pesticide residue contamination has attracted widespread attention and poses a risk to human health. The current traditional pesticide residue detection methods have difficulty meeting rapid and diverse field screening requirements. Microfluidic technology integrates functions from sample preparation to detection, showing great potential for quick and accurate high‐throughput detection of pesticide residues. This paper reviews the latest research progress on microfluidic technology for pesticide residue detection. First, the commonly used microfluidic materials are summarized, including silicon, glass, paper, polydimethylsiloxane, and polymethyl methacrylate. We evaluated their advantages and disadvantages in pesticide residue detection applications. Second, the current pesticide residue detection technology based on microfluidics and its application to real samples are summarized. Finally, we discuss this technology's present challenges and future research directions. This study is expected to provide a reference for the future development of microfluidic technology for pesticide residue detection.

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“…It is a charting tool that can print or plot two-dimensional items on a plane. By altering the type of plotter head being used, one can switch between plotting and printing [ 25 ]. Fabrication of PADs often involves the employment of a spray nozzle that emits an ink stream.…”

Section: Fabricationmentioning

confidence: 99%

Paper based microfluidic devices: a review of fabrication techniques and applications

Anushka

Bandopadhyay

Das

2022

Eur. Phys. J. Spec. Top.

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A wide range of applications are possible with paper-based analytical devices, which are low priced, easy to fabricate and operate, and require no specialized equipment. Paper-based microfluidics offers the design of miniaturized POC devices to be applied in the health, environment, food, and energy sector employing the ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment free and Deliverable to end users) principle of WHO. Therefore, this field is growing very rapidly and ample research is being done. This review focuses on fabrication and detection techniques reported to date. Additionally, this review emphasises on the application of this technology in the area of medical diagnosis, energy generation, environmental monitoring, and food quality control. This review also presents the theoretical analysis of fluid flow in porous media for the efficient handling and control of fluids. The limitations of PAD have also been discussed with an emphasis to concern on the transformation of such devices from laboratory to the consumer.

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Paper-based microfluidic devices: Fabrication, detection, and significant applications in various fields

Cited by 32 publications

References 119 publications

Biomarker Detection in Early Diagnosis of Cancer: Recent Achievements in Point-of-Care Devices Based on Paper Microfluidics

Biomarker Detection in Early Diagnosis of Cancer: Recent Achievements in Point-of-Care Devices Based on Paper Microfluidics

Research progress on pesticide residue detection based on microfluidic technology

Paper based microfluidic devices: a review of fabrication techniques and applications

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