Paper-based microfluidic devices for glucose assays employing a metal-organic framework (MOF)

Ilacas, Grenalynn; Basa, Alexis; Nelms, Katherine J.; Sosa, Joshua D.; Liu, Yangyang; Gomez, Frank A.

doi:10.1016/j.aca.2019.01.009

Cited by 52 publications

(24 citation statements)

References 70 publications

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“…The GOx@MOFs species placed between the paper layers reacted with the glucose and KI solutions flowing through the device, producing a yellow-brown color. This device was dried, scanned, and examined, and a relationship between glucose concentrations and average inverse yellow intensity was discovered 180 . The devices created using MOFs as biomimetic catalysts should broaden the scope of microfluidic technologies for multiplex analyte detection.…”

Section: Mof-based Microfluidic Sensorsmentioning

confidence: 99%

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Microfluidic sensors based on two-dimensional materials for chemical and biological assessments

2022

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Section: Mof-based Microfluidic Sensorsmentioning

confidence: 99%

“…This device was dried, scanned, and examined, and a relationship between glucose concentrations and average inverse yellow intensity was discovered. 180 The devices created using MOFs as biomimetic catalysts should broaden the scope of microfluidic technologies for multiplex analyte detection.…”

Section: Mof-based Microfluidic Sensorsmentioning

confidence: 99%

Microfluidic sensors based on two-dimensional materials for chemical and biological assessments

2022

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“…cancer, non‐communicable diseases, and metabolic disorders) relating to current life‐styles of the world population. Tables and describe the target biomarkers, types of paper substrates, fabrication, and detection techniques, analytical performance characteristics with their respective applications in real sample matrices, for tumor marker and other diseased‐related biomarker detection, respectively. Highlights of selected examples are discussed.…”

Section: Applications For Biomarker Detectionmentioning

confidence: 99%

Recent applications of paper‐based point‐of‐care devices for biomarker detection

Suntornsuk

2019

Electrophoresis

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Detection of biomarkers is essential for diagnosis and prognosis of diseases for healthcare teams to provide timely appropriate treatments. Reliable, inexpensive, and sensitive devices are desirable to serve this purpose. Paper‐based analytical devices (PADs) have gained enormous attention during the past decade as point‐of‐care devices for biomarker detection due to their simplicity, portability, and biocompatibility. Importantly, the devices highly comply with the WHO “ASSURED” concept (i.e. Affordable, Sensitive, Specific, User‐friendly, Rapid and Robust, Equipment free, and Deliverable to end‐users). Thus, PADs could be sustainably alternative tools for biomarker detection, especially in resources‐constraint areas where budget, skillful operators, and health infrastructure are limited. First, this review introduces overviews of biomarkers, their detection and brief history of PADs. Second, description of common fabrication and detection techniques in PADs are provided. Then, it highlights recent state of the art technologies and applications of PADs for various biomarker detection published during 2018 to May 2019. Applications for tumor marker, cardiac and coronary heath disease, and metabolic disorder biomarker detection are tabulated and selected examples are described in details. Finally, it discusses the current challenges, advances, and novel applications of PADs. The review would be valuable for healthcare workers using PADs as cost‐effective point‐of‐care devices for biomarker detection and for researchers working on future developments of the devices.

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“…Filter paper (FP) consists of a cellulose fiber web and has high mechanical stability and tensile strength; it is a common material used in filtration and separation applications in scientific research. It has received considerable attention in microfluidic platforms because of its abundance, low cost, hydrophilic properties, biocompatibility, and ease of modification (He et al, 2015;Ilacas et al, 2019). Paper-based ELISA is the classic paper analytical device: it retains the sensitivity and specificity of traditional ELISA and has the advantages of rapid processing, low solution use, and cost effectiveness of FP (Wang et al, 2012;Busin et al, 2018;Yang et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

A simple and rapid immunochromatography test based on readily available filter paper modified with chitosan to screen for 13 sulfonamides in milk

Zeng¹,

Liang²,

Zheng³

et al. 2021

Journal of Dairy Science

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In this study, we developed a novel, simple, rapid, and low-cost colloidal gold-based immunochromatography method, with filter paper replacing nitrocellulose membrane as the substrate. To obtain adequately immobilized protein, chitosan was used to functionalize the filter paper. After conditions and parameters were optimized, the novel immunochromatography method was applied for detection of sulfonamide residues in milk. Quantitative detection was accomplished using a smartphone and Photoshop software (Adobe Inc., San Jose, CA), allowing us to screen 13 sulfonamides with a limit of detection ranging from 0.42 to 8.64 μg/L and recovery ranging from 88.2 to 116.9% in milk. The proposed novel method performed similarly to the conventional method that uses a nitrocellulose membrane as the transport medium, and it had lower cost and better usability because of the inexpensive and easily available filter paper.

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Paper-based microfluidic devices for glucose assays employing a metal-organic framework (MOF)

Cited by 52 publications

References 70 publications

Microfluidic sensors based on two-dimensional materials for chemical and biological assessments

Microfluidic sensors based on two-dimensional materials for chemical and biological assessments

Recent applications of paper‐based point‐of‐care devices for biomarker detection

A simple and rapid immunochromatography test based on readily available filter paper modified with chitosan to screen for 13 sulfonamides in milk

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