Papillary Carcinoma Thyroid With Uveal Metastases

Abstract

Ocular metastases secondary to thyroid cancer are extremely uncommon, typically affecting the orbit rather than the globe and uvea. Within the uveal structures, the choroid is more commonly involved than the iris and ciliary body. We present a 56-year-old male patient who underwent total thyroidectomy for metastatic papillary thyroid carcinoma (PTC), solid variant. Whole-body(131) I (WBI) scintigraphy was performed and the patient was treated twice with high-dose (131)I therapy. WBI after the second treatment demonstrated right orbital activity. The patient developed sudden onset of right eye diminished vision and was diagnosed with uveal (choroidal) metastases from PTC.

Choroidal Metastasis of Papillary Thyroid Carcinoma Demonstrated on SPECT-CT

“…Of the intraocular metastasis, 88% is to the posterior uvea, 9% is to the anterior uvea (iris), and 2% is to the ciliary body. 5,8 …”