Papillary thyroid carcinoma presenting as acute suppurative thyroiditis: A case report and review of the literature

Puthanpurayil, Shabana Kalladi; Francis, Gary L.; Kraft, Adele; Prasad, Uma R.; Petersson, Rajanya S.

doi:10.1016/j.ijporl.2017.11.032

Cited by 14 publications

(10 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…AST and thyroid abscess usually present with an acutely enlarging neck mass. The main causes are pyriform sinus fistula related to anomalies of the third and fourth branchial pouches [22], following neoplastic thyroid nodule [21, 22], Hashimoto thyroiditis [23], and penetration of the thyroid gland by foreign bodies such as fish bones [17]. Underlying comorbidities including tuberculosis, diabetes mellitus, and HIV infection appear to increase the risk of developing thyroid abscess.…”

Section: Discussionmentioning

confidence: 99%

First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm

et al. 2019

View full text Add to dashboard Cite

Background Helicobacter cinaedi is a microaerobic Gram-negative spiral-shaped bacterium that causes enteritis, cellulitis, and bacteremia in both immunocompromised and immunocompetent patients. While there have been increasing numbers of reported H. cinaedi infections recently, there has been no thyroid abscess case caused by H. cinaedi presenting with thyroid storm. Case presentation A 50-year-old Japanese man presented with a 9-day history of high fever associated with palpitations, dry cough, and chronic diarrhea. The patient had a history of Basedow’s disease that had been treated with thiamazole in the past. During the current episode, the patient was diagnosed with thyroid storm and treated accordingly. The blood culture taken on admission was positive for H. cinaedi . This finding was confirmed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOFMS). A systemic computed tomography (CT) scan revealed a thyroid abscess as the site of infection and cause of the bacteremia. The 16S rRNA gene sequencing identified the pathogen of thyroid abscess as H. cinaedi . Clinical symptoms and laboratory data normalized on admission day 7 after treatment with both effective antibiotics and antithyroid drugs. Conclusions The case study described a patient with a history of Basedow’s disease that presented with a thyroid abscess caused by H. cinaedi with symptoms similar to those of thyroid storm. While this bacterium has been implicated in other infections, we believe this is the first time the bacteria has been documented to have caused a thyroid abscess. Electronic supplementary material The online version of this article (10.1186/s12879-019-3808-7) contains supplementary material, which is available to authorized users.

show abstract

Section: Discussionmentioning

confidence: 99%

First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm

et al. 2019

View full text Add to dashboard Cite

show abstract

“…At an ultrasound guided puncture of the thyroid, brownish pus was seen, and a thyroid drain was inserted. TSH was 0.08 mIU/L (0.4-3.5) and free T4 57 pmol/L (8)(9)(10)(11)(12)(13)(14), and po propranolol 20 mg tds was initiated. TRAb and TPOab were negative.…”

Section: Casementioning

confidence: 99%

Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes

Falhammar

Wallin

Calissendorff

2019

Preprint

View full text Add to dashboard Cite

Background Abscess in the thyroid gland is a rare but severe infectious disease. The condition can have anatomic or iatrogenic underlying causes. If untreated it could be fatal. Pathogens vary considerably. Treatment is intravenous antibiotics, drainage, and sometimes surgery. Methods The electronic medical records of all adult patients with acute thyroiditis 2003–2017 treated at the Karolinska University Hospital (catchment area 2 million) in Sweden were systematically reviewed. Results Five patients were found in the catchment area. One patient from another region but known to us was also included. Thus, six patients (aged 28-73 years) were included in the study. Median length of hospital stay was 7.5 days (4-79 days). All were treated with antibiotics (intravenous n=5, oral n=1). Total antibiotic treatment duration was 13.5 days (10-41 days). Blood cultures were positive in three (streptococcus pneumonia, streptococci sanguineous, pepto streptococci), deep tissue culture in three (escherichia coli, candida, hemophilic influenza) and no positive culture at all in two. Drainage was used in three patients. All patients recovered without recurrences. Surgery was performed twice in the acute phase in one. There was no recurrence during 7 years (3-12) of follow-up, but one patient died after three years (severe heart failure and pneumonia). Conclusion Thyroid abscess in adults is extremely rare nowadays in the developed world. With prompt antibiotic therapy, drainage and in some cases thyroidectomy the prognosis seems favourable.

show abstract

“…At an ultrasound guided puncture of the thyroid, brownish pus was seen, and a thyroid drain was inserted. TSH was 0.08 mIU/L (0.4-3.5) and free T4 57 pmol/L (8)(9)(10)(11)(12)(13)(14), and po propranolol 20 mg 6 tds was initiated. TRAb and TPOab were negative.…”

Section: Casementioning

confidence: 99%

“…A previously healthy 28-year old woman had three months after delivery developed left-sided swollenness in the neck, pain, fever and tachycardia in the last 10 days. At another hospital this was suspected as a subacute thyroiditis as TSH was 0.1 mIU/L (0.4-3.5) and free T4 21 pmol/L (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22).…”

Section: Casementioning

confidence: 99%

“…Only 8% of AST occurs in adults [7]. Hashimoto´s disease [8], large goiters [9] or thyroid cancer could predispose individuals [10], but AST could also arise by hematogenous or lymphatic spread or by iatrogenic infections after fine needle aspiration biopsy (FNA) [11]. Multiple pathogens have been implicated, mainly staphylococcus aureus [12] and streptococci species [12,13], but also tuberculosis (sometimes in combination with HIV) [14,15], brucellosis [16], candida [17], salmonella [18], and anaerobes as escherichia coli [19] and klebsiella [20].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes

Falhammar

Wallin

Calissendorff

2019

Preprint

View full text Add to dashboard Cite

Background: Abscess in the thyroid gland is a rare but severe infectious disease. The condition can have anatomic or iatrogenic underlying causes. If untreated it could be fatal. Pathogens vary considerably. Treatment is intravenous antibiotics, drainage, and sometimes surgery. Methods: The electronic medical records of all adult patients with acute thyroiditis 2003-2017 treated at the Karolinska University Hospital (catchment area 2 million) in Sweden were systematically reviewed.Results: Five patients were found in the catchment area. One patient from another region but known to us was also included. Thus, six patients (aged 28-73 years) were included in the study. Median length of hospital stay was 7.5 days (4-79 days). All were treated with antibiotics (intravenous n=5, oral n=1). Total antibiotic treatment duration was 13.5 days (10-41 days). Blood cultures were positive in three (streptococcus pneumonia, streptococci sanguineous, pepto streptococci), deep tissue culture in three (escherichia coli, candida, hemophilic influenza) and no positive culture at all in two. Drainage was used in three patients. All patients recovered without recurrences. Surgery was performed twice in the acute phase in one. There was no recurrence during 7 years (3-12) of followup, but one patient died after three years (severe heart failure and pneumonia). Conclusion: Thyroid abscess in adults is extremely rare nowadays in the developed world. With prompt antibiotic therapy, drainage and in some cases thyroidectomy the prognosis seems favourable.

show abstract

Papillary thyroid carcinoma presenting as acute suppurative thyroiditis: A case report and review of the literature

Cited by 14 publications

References 15 publications

First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm

First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm

Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes

Acute suppurative thyroiditis with thyroid abscess in adults: clinical presentation, treatment and outcomes

Contact Info

Product

Resources

About