Papillary Thyroid Carcinoma Presenting with a Right Preauricular and Intracranial mass

Abstract

Objective: To describe a case of a papillary thyroid carcinoma presenting with a preauricular and an intracranial mass and review the literature on the metastatic nature and invasiveness of papillary thyroid carcinoma. Methods:Design: Case Report Setting: Tertiary Private Hospital Patient: OneResults: A 46-year-old female with a 12-year anterior neck mass and a two-year right pre-auricular pleomorphic adenoma on fine needle aspiration biopsy was found to have an intracranial mass on CT-scan. Total thyroidectomy and section biopsy of the preauricular mass yielded a final histopathologic report of follicular variant of papillary carcinoma, thyroid gland; and metastatic papillary thyroid carcinoma, follicular type, pre-auricular mass. The condition of the patient precluded neurosurgical intervention and RAI therapy and she underwent 23 sessions of external radiotherapy using 46Gy with significant diminution in size of the intracranial metastasis. Conclusion:Papillary thyroid malignancy may be an indolent tumor but it is capable of distant metastasis. We should be alerted by host and tumor factors which can be predictors of a more radical papillary malignant disease whose management entails proper staging evaluation and good communication of prognostic data and available, realistic therapeutic options to patients using a multidisciplinary approach.

Missing Skeletal Muscle Metastases of Papillary Thyroid Carcinoma

“…Nevertheless, having analyzed medical literature as far back as the last hundred and ten years, I have identified in total 58 cases of papillary (PTC) and follicular (FTC) thyroid cancer metastases to skeletal muscles: 45 cases in the considered time range 2006 through 2016, and 13 cases from 1907 to 2005 (doi: 10.3892/ol.2018.8216). Still, considering only the cases of papillary thyroid cancers (PTC) during this period (2006–2016), a total of 34 skeletal muscle metastases were described in 27 patients: 12 females (44%) and 15 males (56%) [ 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. The mean age was 54.7 years (95% CI: 47.6–61.8; range: 25–89).…”