Papillomatosis of larynx and bronchi.Case report with 34-year follow-up

Pulmonary spread of laryngeal papillomatosis: radiological findings

“…Peripheral seeding by tracheostomy or surgical manipulation and the multicentric origin of papillomas have been advanced as possible explanations. 14,20 Kramer et al 9 speculated that detached fragments, particularly during endoscopic resection, are carried down the airway by airflow. Furthermore, those that lodge proximal to the respiratory bronchioles may be removed by mucociliary action and coughing.…”

Successful Treatment of Juvenile Laryngeal Papillomatosis-Related Multicystic Lung Disease With Cidofovir

“…20 Chest radiographs have shown persistent postobstructive atelectasis, 7,10 recurrent airspace consolidation, 6,10,11,18 recurrent pneumothoraces, 1 and nodules with and without cavitation. 6,8,[12][13][14]17 Chest CT scans have demonstrated multiple nodules, with or without cavitation, as well as thin-walled cysts.…”

Papillomatous Granulomatosis (Florid Oral Papillomatosis).

“…Putney (1955) and in the bronchi by Moore and Lattes (1959). In a series of 501 cases of papilloma of the larynx Putney found papillary carcinoma in 5% of the cases.…”

“…In nine cases it was evident that malignancy developed from a pre-existing papilloma. Moore and Lattes (1959) emphasized that simultaneous existence of laryngeal and pulmonary papilloma is extremely rare. One of these exceptional cases was reported by R. Stein and B. Yolk (1959).…”