Parameters for Fabricating Nano-Au Colloids through the Electric Spark Discharge Method with Micro-Electrical Discharge Machining

Tseng, Kuo-Hsiung; Chung, Meng-Yun; Chang, Chaur-Yang

doi:10.3390/nano7060133

Cited by 26 publications

(9 citation statements)

References 19 publications

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“…Nanometal colloids, such as nanogold, nanosilver, nano-copper, nano-aluminum, and nano-titanium, can be made with any method able to conduct electricity using an EDM [ 26 , 27 , 28 , 29 , 30 ]. Nanosilver colloids have been applied in biomedical research, and silver ions can resist bacteria growth.…”

Section: Methodsmentioning

confidence: 99%

Implementation of Micro-EDM Monitoring System to Fabricate Antimicrobial Nanosilver Colloid

Tseng

Chung

Chiu³

2022

Micromachines

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This study implemented a discharge energy and success-rate monitoring system to replace the traditional oscillograph observation method and conducted a microbial control test for a nanosilver colloid prepared by an Electrical Discharge Machine (EDM). The advantage of this system is that the discharge conditions can be instantly and continuously observed, and the optimized discharge parameter settings can be recorded. The monitoring system can use the arcing rate to control the energy consumption of the electrodes to standardize the nanosilver colloid. The results show that the arcing rate, electrode weight loss, and absorption peak wavelength are very accurate. The nanosilver colloid prepared by EDM is free of any chemical additive, and in comparison to other preparation methods, it is more applicable to biotechnology, even to the human body. The microbial control test for the nanosilver colloid included a Bathroom sample, Penicillium, Aspergillus niger, and Aspergillus flavus. In test solution NO.1 (prepared by micro-EDM), the effects of all four samples were inhibited at 14mm in a metal ring experiment, and in the cotton pad experiment, Penicillium was inhibited at 17 mm. In the metal ring experiment, test solution NO. 2 (prepared by EDM) had an effect at 20 mm on the bathroom samples, but at only 15 mm on flavus. In the cotton pad experiment, the inhibited effect was more effective in Penicillium and Aspergillus Niger; both inhibited effects occurred at 25 mm. Test solutions NO.3 (prepared by micro-EDM) and NO.4 (32 ppm Ag+) had a 14–15 mm effect on all samples in the metal ring experiment. In the cotton pad experiment, NO.3 had an effect on Penicillium at 19 mm while the effect on the others occurred at 14 mm, and NO.4 had an effect at 25 mm in Penicillium and Aspergillus Niger, and only at 14 mm in the bathroom and Aspergillus flavus samples.

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Section: Methodsmentioning

confidence: 99%

Implementation of Micro-EDM Monitoring System to Fabricate Antimicrobial Nanosilver Colloid

Tseng

Chung

Chiu³

2022

Micromachines

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“…The toxicity is likely due to one or more of the following: cellular rate of uptake, increase in cell membrane permeability, changes to nanoparticle size and morphology, altered dispersion or agglomeration and rate of dissolution. It has been reported that NPs can be prepared using an electrical discharge [44][45][46]. We therefore investigated the effect of CAP on AgNP.…”

Section: The Effect Of Cap On Agnp Sizementioning

confidence: 99%

Cold Atmospheric Plasma induces silver nanoparticle uptake, oxidative dissolution and enhanced cytotoxicity in Glioblastoma multiforme cells

Manaloto

Gowen²,

Leśniak³

et al. 2020

Preprint

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Running title: Cold Atmospheric Plasma enhances silver nanoparticle uptake and cytotoxicity.2 Abstract Silver nanoparticles (AgNP) emerged as a promising reagent for cancer therapy with oxidative stress implicated in the toxicity. Meanwhile, studies reported cold atmospheric plasma (CAP) generation of reactive oxygen and nitrogen species has selectivity towards cancer cells. Gold nanoparticles display synergistic cytotoxicity when combined with CAP against cancer cells but there is a paucity of information using AgNP, prompting to investigate the combined effects of CAP using dielectric barrier discharge system (voltage of 75 kV, current is 62.5mA, duty cycle of 7.5kVA and input frequency of 50-60Hz) and 10nm PVA-coated AgNP using U373MG Glioblastoma Multiforme cells. Cytotoxicity in U373MG cells was >100-fold greater when treated with both CAP and PVA-AgNP compared with either therapy alone (IC 50 of 4.30 µg/mL with PVA-AgNP alone compared with 0.07 µg/mL after 25s CAP and 0.01 µg/mL 40s CAP). Combined cytotoxicity was ROS-dependent and was prevented using N-Acetyl Cysteine. A novel darkfield spectral imaging method investigated and quantified AgNP uptake in cells determining significantly enhanced uptake, aggregation and subcellular accumulation following CAP treatment, which was confirmed and quantified using atomic absorption spectroscopy. The results indicate that CAP decreases nanoparticle size, decreases surface charge distribution of AgNP and induces uptake, aggregation and enhanced cytotoxicity in vitro.

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“…With the increasing market demand for miniaturization and the precision of products, micro-processing technology has become one of the important indicators to measure a country's scientific and technological strength [1][2][3]. Micro-electrical discharge machining (micro-EDM) has become one of the most popular microfabrication technologies due to the advantage of machining electrically conductive materials without direct contact [4][5][6]. Micro-EDM has been has attracted great attention from researchers and has been widely used in the micro-machining field [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Study on the Discharge Characteristics of Single-Pulse Discharge in Micro-EDM

Liu

Zhang

et al. 2020

Micromachines

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To further study the discharge characteristics and machining mechanism of micro-electrical discharge machining (micro-EDM), the variation trends of the discharge energy and discharge crater size with actual discharge duration are discussed based on single-pulse experiments. The polarity effect of micro-EDM was analyzed according to the motion characteristics of electrons and ions in the discharge plasma channel. The results show that the discharge current and voltage of micro-EDM were independent of the discharge width and open-circuit voltage. The energy utilization rate of the short-pulse discharge was relatively high, and the energy utilization rate decreased gradually as the discharge duration increased. Even if the mass of the positive ion was much larger than that of the electron, the kinetic energy of the positive ion was still less than that of the electron when bombarding the surface of the electrode. The acceleration and speed of electrons were very high, and the number of times that electrons bombarded the surface of positive electrode was more than 600 times that of positive ions bombarding the surface of the negative electrode during the same time.

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Parameters for Fabricating Nano-Au Colloids through the Electric Spark Discharge Method with Micro-Electrical Discharge Machining

Cited by 26 publications

References 19 publications

Implementation of Micro-EDM Monitoring System to Fabricate Antimicrobial Nanosilver Colloid

Implementation of Micro-EDM Monitoring System to Fabricate Antimicrobial Nanosilver Colloid

Cold Atmospheric Plasma induces silver nanoparticle uptake, oxidative dissolution and enhanced cytotoxicity in Glioblastoma multiforme cells

Study on the Discharge Characteristics of Single-Pulse Discharge in Micro-EDM

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