Paranasal Sinus Osteomas and Gardner's Syndrome

Abstract

Otolaryngologists should be aware of the possibility of Gardner's syndrome in patients with paranasal sinus osteomas. Suspected patients should have a complete workup for Gardner's syndrome, including lower gastrointestinal tract endoscopy, barium enema imaging, and DNA testing.

Middle Turbinate Osteoma

“…In affected individuals, the risk of developing colon cancer approaches 100%. On average, osteomas are detected 17 years before colon polyps begin to appear (8, 9). In turbinate osteomas, no associated history of facial trauma or nasal surgery had been reported, and paranasal sinus infection appears to be the result of sinus meatal obstruction due to mass effect of the tumor (3).…”

“…In osteoma arising from the paranasal sinuses, surgical removal is indicated if it extends beyond the boundaries of the sinus, continues to enlarge, localizes in the region adjacent to the naso-frontal duct, or if signs of chronic sinusitis are present, regardless of size in symptomatic tumors (6-8). …”

Bicoronal approach in managing frontal sinus osteoma – case report

“…7 Some authors connect osteomas to Gardner's syndrome. 8 There are three histological types of osteomas: ivory osteoma (dense compact bone), mature osteoma (trabecular bone) and mixed type.…”

Case report. Giant ethmoido-frontal osteoma with intracranial and orbital extension – Case report

“…Also, osteomas can be found in Gardner's syndrome, an autosomal dominant disorder (intestinal polyposis, cutaneous tumors, osteomas). For this reason, all patients suspected of an osteoma should undergo a colonoscopy (which we have recommended to our patient, with a negative result) 8 . The gold standard of diagnosis is computed tomography.…”