Paratesticular Liposarcoma: A Case Report and Review of the Literature

Abstract

Introduction. Liposarcoma is a rare pathological entity. By far it is the most common histological subtype of genitourinary sarcomas in adults. Approximately two hundred cases were reported in the literature. We are hereby presenting a case with a typical clinical scenario of paratesticular liposarcoma. Case report. A 75-year-old gentleman presented with a painless right hemiscrotal swelling that was progressively increasing in size over the last 6 years. Testicular tumour markers were negative. Imaging showed a heterogenous mass with fat component. Subsequently he underwent wide local excision that included the paratesticular mass along with the right testicle and all right inguinal canal contents up to the deep inguinal ring with the sparing of right illioinguinal nerve. Histopathological examination showed a well differentiated liposarcoma of the spermatic cord. He remained recurrence-free so far after 18 months of followup. Conclusion. Radical orchidectomy with wide local excision comprises the cornerstone of treatment of paratesticular liposarcoma. Due to the rarity of the disease there is no definite universal consensus of opinion as regards the role of radiotherapy and chemotherapy.

Giant paratesticular liposarcoma: A case report and review of the literature

“…Compared to subcutaneous fatty tissue, CT usually demonstrates the tumor area with lower density. It may be helpful to establish tumor location, tissue characteristics, staging and follow-up (8,16,23). MRI, the golden standard in staging soft tissue tumors, not only provides clear information on the tumor foci but also characterizes and delineates the degree of local tumor extension (9,14,20).…”

“…There is a general consensus that radical orchiectomy with wide local excision and high ligation of the spermatic cord are the current standard treatment strategies due to frequent recurrence that associated with incomplete excision (7)(8)(9)20). Because the clinical presentation of PLS is similar to scrotal lipoma or groin hernia, Immediate radical procedure should be performed to avoid the high risk of local recurrence and involvement of worsening prognosis, when a suspicious PLS is diagnosed.…”

“…However, whether radiotherapy should be used as postoperative routine therapy remains to be discussed because recurrent tumor after radiotherapy may be more aggressive (10). Some suggested that radiotherapy should be used for local control (8,10,14,30). There are no large studies with respect to the results of chemotherapy.…”

“…Giant PLS is more rare with only a few cases having been reported (2)(3)(4)(5)(6). Due to the rarity of the disease, there is no standardized guideline as regards its incidence, diagnosis, recurrence and treatment (7,8). In this study, we present a case of a giant dedifferentiated PLS of the right testis with magnetic resonance imaging (MRI) measuring 7.8x5.8x10.4 cm and focus on the discussion about the clinical characteristics, diagnosis and treatment of this disease.…”

Atypical lipomatous tumour of the round ligament – report of a rare case with review of literature

“…However, radiotherapy may be recommended in case of positive margins, recurrences or aggressive histology [7]. Prognosis of ALTs is good owing to low risk of metastasis.…”