Parietal and early visual cortices encode working memory content across mental transformations

Christophel, Thomas B.; Cichy, Radoslaw Martin; Hebart, Martin N.; Haynes, John­–Dylan

doi:10.1016/j.neuroimage.2014.11.018

Cited by 94 publications

(105 citation statements)

References 53 publications

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“…Statistics for each IPS subregion can be found in Table S1. Collectively, these results are consistent with earlier studies documenting stimulus-specific representations in posterior IPS (e.g., Christophel et al, 2012, 2015). …”

Section: Resultssupporting

confidence: 92%

“…Previous studies have successfully decoded and/or reconstructed representations of remembered features based on activation patterns in occipital cortex (V1-hV4v/V3a; Serences et al, 2009; Harrison and Tong, 2009; Riggall and Postle, 2012; Ester et al, 2013; Emrich et al, 2013) and posterior parietal cortex (Christophel et al, 2012, 2015). Consequently, we first attempted to reconstruct representations of the remembered and non-remembered orientations within these regions.…”

Section: Resultsmentioning

confidence: 99%

“…More recent human neuroimaging studies have used multivariate analyses to successfully decode simple visual features or spatial positions held in WM from delay-period multivoxel activation patterns in regions of posterior occipital and parietal cortex (see Serences et al, 2009; Harrison and Tong, 2009; Ester et al, 2009; Riggall and Postle, 2012; Emrich et al, 2013; Christophel et al, 2012, 2015; Jerde et al, 2012; Saber et al, 2015). Importantly, sustained activity changes can be dissociated from information storage during WM, as decoding is often successful even though the amplitude of the blood-oxygenation-level-dependent (BOLD) response typically returns to baseline levels during the memory delay period (Serences et al, 2009; Harrison and Tong, 2009; Riggall and Postle, 2012; Emrich et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Parietal and Frontal Cortex Encode Stimulus-Specific Mnemonic Representations during Visual Working Memory

Ester

Sprague

Serences

2015

Neuron

374

339

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Summary Working memory (WM) enables the storage and manipulation of information in an active state. WM storage has long been associated with sustained increases in activation across a network of frontal and parietal cortical regions. However, recent evidence suggests that these regions primarily encode information related to general task goals rather than feature-selective representations of specific memoranda. These goal-related representations are thought to provide top-down feedback that coordinates the representation of fine-grained details in early sensory areas. Here, we test this model using fMRI-based reconstructions of remembered visual details from region-level activation patterns. We could reconstruct high-fidelity representations of a remembered orientation based on activation patterns in occipital visual cortex and in several sub-regions of frontal and parietal cortex, independent of sustained increases in mean activation. These results challenge models of WM that postulate disjoint frontoparietal “top-down control” and posterior sensory “feature storage” networks.

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Section: Resultssupporting

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Parietal and Frontal Cortex Encode Stimulus-Specific Mnemonic Representations during Visual Working Memory

Ester

Sprague

Serences

2015

Neuron

374

339

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“…Also, converging findings on the specific role of spatial abilities have been obtained by using nonverbal executive control and working memory tasks (see Mäntylä, 2013;Todorov et al, 2014). Thus, the fact that coordinate processing contributed to multitasking performance beyond MRT in Study 2 is particularly interesting, because previous research showed that mental rotation processes place demands upon executive processes (Bruyer & Scailquin, 1998;Cornoldi & Mammarella, 2014;Salway & Logie, 1995) as well as involving VSWM, when keeping in mind the products of multiple rotation steps (Bauer & Jolicouer, 1996;Christophel, Cichy, Hebart & Haynes, 2015).…”

Section: Discussionmentioning

confidence: 89%

Deadlines in space: Selective effects of coordinate spatial processing in multitasking

et al. 2015

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Many everyday activities require coordination and monitoring of multiple deadlines. One way to handle these temporal demands might be to represent future goals and deadlines as a pattern of spatial relations. We examined the hypothesis that spatial ability, in addition to executive functioning, contributes to individual differences in multitasking. In two studies, participants completed a multitasking session in which they monitored four digital clocks running at different rates. In Study 1, we found that individual differences in spatial ability and executive functions were independent predictors of multiple-task performance. In Study 2, we found that individual differences in specific spatial abilities were selectively related to multiple-task performance, as only coordinate spatial processing, but not categorical, predicted multitasking, even beyond executive functioning and numeracy. In both studies, males outperformed females in spatial ability and multitasking and in Study 2 these sex differences generalized to a simulation of everyday multitasking. Menstrual changes moderated the effects on multitasking, in that sex differences in coordinate spatial processing and multitasking were observed between males and females in the luteal phase of the menstrual cycle, but not between males and females at menses. Overall, these findings suggest that multiple-task performance reflects independent contributions of spatial ability and executive functioning. Furthermore, our results support the distinction of categorical versus coordinate spatial processing, and suggest that these two basic relational processes are selectively affected by female sex hormones and differentially effective in transforming and handling temporal patterns as spatial relations in the context of multitasking.

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“…In the area MT+/V5, significantly discriminative brain activity was only found by RSLDA (51.2% ± 0.3). However, given the nature of the classification task -based on classification of single trials in a fast event-related design -low accuracies are not surprising and should not be interpreted as reflecting low power (Christophel et al, 2015).…”

Section: Relevance Subclass Lda (Rslda)mentioning

confidence: 99%

Analyzing neuroimaging data with subclasses: A shrinkage approach

et al. 2016

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Parietal and early visual cortices encode working memory content across mental transformations

Cited by 94 publications

References 53 publications

Parietal and Frontal Cortex Encode Stimulus-Specific Mnemonic Representations during Visual Working Memory

Parietal and Frontal Cortex Encode Stimulus-Specific Mnemonic Representations during Visual Working Memory

Deadlines in space: Selective effects of coordinate spatial processing in multitasking

Analyzing neuroimaging data with subclasses: A shrinkage approach

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