Parsonage–Turner syndrome: A rare case of abacavir hypersensitivity reaction in HIV-infected patients

Bellagamba, Rita; Tommasi, Chiara; Marco, Michele De; Narciso, Pasquale

doi:10.1016/j.jinf.2008.05.001

Cited by 13 publications

(10 citation statements)

References 13 publications

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“…La phase hyperalgique dure de quelques jours à trois semaines, des périodes douloureuses plus longues, jusqu'à trois mois, ayant pu être rapportées. Les étiologies sont multiples : suite d'un traumatisme, d'une intervention chirurgicale ; survenue après une vaccination ou encore après une prise médicamenteuse, notamment une prise d'antisyphilitiques ou d'antiviraux comme l'Abacavir [2]. Une maladie de système (lupus ; périartérite noueuse), une infection peuvent être discutées.…”

Section: Discussionunclassified

“…Les [1]. La revue de la littérature des cas de syndrome de Parsonage-Turner rapportés au VIH, permet de discuter sept dossiers [2][3][4][5][6] ; l'atteinte serait plus volontiers bilatérale dans cette étiologie rétrovirale. Le syndrome de Parsonage-Turner révèle la maladie virale six fois.…”

Section: Discussionunclassified

“…Le syndrome de Parsonage-Turner révèle la maladie virale six fois. Pour le dernier dossier, rapporté par Bellagamba et al en 2008 [2], ce syndrome apparaît au cours d'une infection VIH avancée : ces auteurs avancent le rôle direct de l'agent viral en raison d'une charge virale initiale très élevée, mais aussi celui de l'Abacavir, traitement antirétroviral, par l'intermédiaire d'une éventuelle réaction d'hypersensibilité. L'étude du LCR fut réalisée quatre fois, avec trois fois une discrète pléïocytose et une dissociation albumino-cytologique pour le quatrième dossier.…”

Section: Discussionunclassified

“…Le traitement du syndrome de Parsonage-Turner ne fait pas l'objet de consensus. La prise en charge doit avant tout être symptomatique : traitement antalgique allant jusqu'aux morphiniques, parfois associé à un traitement anti-inflammatoire ou à un traitement visant les douleurs neuropathiques ; traitement orthopédique avec immobilisation puis rééducation motrice [2]. À côté de ce traitement symptomatique, la prise en charge comporte aussi la mise en route d'un traitement de l'affection causale, avec une trithérapie antirétrovirale.…”

Section: Discussionunclassified

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Syndrome de Parsonage et Turner révélant une primo-infection à VIH

Depreux

Rabar

Bruneau

et al. 2012

Médecine et Maladies Infectieuses

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Section: Discussionunclassified

See 2 more Smart Citations

Syndrome de Parsonage et Turner révélant une primo-infection à VIH

Depreux

Rabar

Bruneau

et al. 2012

Médecine et Maladies Infectieuses

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“…12 Entre outros fatores de risco relatados, estão a utilização de determinadas drogas (heroína) e doenças crônicas como diabetes, artrite reumatoide, síndrome de Guillain-Barré, arterites e linfoma. [13][14][15][16][17] Estudos histológicos demonstraram a evidência de uma etiologia autoimune. Um estudo mostrou que os linfócitos de pacientes acometidos apresentavam aumento da sua atividade proliferativa (isto é, a transformação de linfócitos pequenos em células maiores que são capazes de sofrer mitose) em culturas com extratos de diferentes nervos do plexo braquial e seus ramos, mas não em culturas com extratos de nervos dos plexos sacrais.…”

Section: Etiologiaunclassified

A “corrida” pela vacina da gripe em 2016

Silva

2016

Rev. Fac. Ciênc. Méd. Sorocaba

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Parsonage-Turner syndrome RESUMOA síndrome de Parsonage-Turner, neuralgia amiotrófica ou neurite do plexo braquial é uma síndrome rara, cuja causa é desconhecida. Os nervos supraescapular, axilar e seus músculos correspondentes são afetados com maior frequência. A doença apresenta uma ampla gama de manifestações clínicas, e os pacientes geralmente apresentam-se aos médicos de diferentes especialidades com queixa de dor intensa, de início súbito no ombro, que irradia para o braço ou pescoço e dura por horas ou semanas. Quando a dor desaparece, desenvolve-se uma paralisia flácida com fraqueza e atrofia muscular associada à perda sensorial da cintura escapular. O diagnóstico preciso pode ser desafiador e requer uma história completa e exame físico detalhado. Estudos de velocidade de condução nervosa e imagem auxiliam na avaliação. O tratamento consiste no controle sintomático. Os sintomas podem persistir durante mais do que um ano, mas a maioria dos pacientes evolui para resolução ao longo do tempo. Palavras-chave: neurite do plexo braquial; plexo braquial; inflamação. ABSTRACTThe Parsonage-Turner syndrome, amyotrophic neuralgia or neuritis of the brachial plexus is a rare syndrome, of unknown cause. The more frequently affected structures are the suprascapular, axillary nerves and their corresponding muscles. The disease has a wide range of clinical manifestations, and patients usually come to physicians of different specialties with intense and sudden pain complaints in the shoulder, radiating to the arm or neck and that lasts for hours or weeks. When the pain disappears, the patient develops a flaccid paralysis and muscle weakness associated with sensory loss of the shoulder girdle. Accurate diagnosis can be challenging and requires a complete history and detailed physical examination. Nerve conduction velocity and imaging studies help to evaluate the disease. Treatment consists of symptomatic control. The symptoms can persist for more than one year, but most patients recover over time.

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Current awareness: Pharmacoepidemiology and drug safety

2009

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 23 sections: 1 Reviews; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Antidiabetic Agents; 21 Contrast Agents; 22 Bone Conservation Agents; 23 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Parsonage–Turner syndrome: A rare case of abacavir hypersensitivity reaction in HIV-infected patients

Cited by 13 publications

References 13 publications

Syndrome de Parsonage et Turner révélant une primo-infection à VIH

Syndrome de Parsonage et Turner révélant une primo-infection à VIH

A “corrida” pela vacina da gripe em 2016

Current awareness: Pharmacoepidemiology and drug safety

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