Passive immune transfer in fat-tailed sheep: Evaluation with different methods

Brujeni, Gholamreza Nikbakht; Jani, Sarmen Shahi; Alidadi, Nasser; Tabatabaei, Saeid; Sharifi, Hamid; Mohri, Mehrdad

doi:10.1016/j.smallrumres.2009.12.024

Cited by 11 publications

(14 citation statements)

References 12 publications

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“…In this study mean SIgGC-24 determined before colostrums intake was in agreement with previous reports [5,21] and increased significantly after colostrum ingestion. The IgG concentration of day 1 was similar to that reported previously by researchers [5,22,27] but lower than that of others [16,21,28] . This variation might be related to the number of subjects investigated as previous studies used small number of animals, controlled colostrum intake and farm management system (vaccination, good hygiene and feeding practices etc.)…”

Section: Gökçe Ataki̇şi̇supporting

confidence: 88%

“…Inability of neonatal lambs to obtain and absorb sufficient amount of colostral IgG is a secondary immunodeficiency disorder termed as Failure of Passive Transfer (FPT). FPT results in hypogammaglobulinemia which in turn predisposes neonates to develop diseases and death [1,2,5,[8][9][10][11][12][13][14][15][16] . Therefore, passive immunity plays a critical determining role in the short-term health and survival for lambs until their own immune system begins functioning fully.…”

Section: Introductionmentioning

confidence: 99%

“…Therefore, passive immunity plays a critical determining role in the short-term health and survival for lambs until their own immune system begins functioning fully. Numerous studies in the past three decades correlated neonatal diseases with inadequate serum IgG, in other words, FPT in animals and thus suggested the importance of IgG in the prevention of infections and enhancing growth performance in neonates [1,2,5,8,9,14,[16][17][18] .…”

Section: Introductionmentioning

confidence: 99%

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Kuzularda Serum ve Kolostral IgG (Pasif İmmünite) Konsantrasyonlarının Total Protein ve Sağlık İle İlişkisi

Atakisi¹

2018

Kafkas Univ Vet Fak Derg

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This study was designed to determine relationship between sheep serum before lambing, colostrum and 1-day-old lamb serum total protein (TP) and immunoglobulin-G (IgG) concentration and their effect on neonatal diseases and also the linear relationship between serum TP and IgG concentration (STPC and SIgGC, respectively) in different days of the neonatal period thereby determining the feasibility of TP concentration in the prediction of colostrum quality and passive immunity and to define a cutoff point for STPC and SIgGCat 24 h after birth (STPC-24 and SIgGC-24, respectively) associated with increased risk of illness or death in lambs. For this purpose, blood was obtained from the lambs and ewes at day 1 (n=325), at day 0 (before colostrum intake) and on different days in neonatal periods (n=50) and blood (10-15 days before lambing) and colostrum were obtained from the respective ewes related to the lambs. Mean serum TP and IgG concentrations on days 1, 2, 4, 7, 14 and 28 were significantly higher than values on day 0 (before colostrum intake) from the lambs remained healthy in neonatal period. The STPC-24 was significantly lower in diseased and dead lambs when compared to healthy lambs in the neonatal period (P<0.001 and P<0.001 respectively). The STPC-24 in lambs that died or became ill was 62% to 67% in SIgGC-24, respectively. Mean colostral TPC was significantly (P<0.05) higher in dams (n=254) of healthy lambs when compared to those of sick lambs in neonatal period. There was a significant correlation between the dams' STPC and both the SIgGC in dams and SIgGC-24 in their lambs (R=0.454, R=0.342, respectively). The study revealed that STPC-24 >55 g/L and SIgGC-24>600 mg/ dL is probably consistent with adequate level of passive transfer. It was also noted that in addition to determining colostrum quality, STPC plays an essential role in the prediction and prevention of neonatal diseases in lambs. In conclusion, immediate and inexpensive determination of TP concentrations is beneficial in making timely management and treatment decisions related to failure of passive transfer (FPT).

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Section: Gökçe Ataki̇şi̇supporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Kuzularda Serum ve Kolostral IgG (Pasif İmmünite) Konsantrasyonlarının Total Protein ve Sağlık İle İlişkisi

Atakisi¹

2018

Kafkas Univ Vet Fak Derg

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“…As it was described by Brujeni et al (2010) and Ciupersescu (1977), sex was not taken into consideration to simplify the analysis, because no influence was detected. The SAS PROC MIXED procedure for repeated measures was used to evaluate the fixed effect of rearing system, time and the interaction between both effects (rearing system × time) on plasma IgG and IgM concentrations, complement system activity and BW evolution of lambs from birth to weaning.…”

Section: Methodsmentioning

confidence: 99%

The effect of colostrum period management on BW and immune system in lambs: from birth to weaning

Hernández-Castellano

Suárez-Trujillo

Martell-Jaizme

et al. 2015

Animal

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The aim of this study was to investigate the BW and immune status of lambs reared under natural conditions or under artificial conditions fed two different colostrum amounts. In this study, 60 lambs were randomly divided into groups according to treatment. Twenty lambs remained with their dams (natural rearing (NR) group). Forty lambs were removed from their dams at birth. Lambs were bottle-fed with a pool of sheep colostrum, receiving either 4 g of IgG/kg of BW at birth (C4 group) or 8 g of IgG/kg of BW at birth (C8 group). The total colostrum amount was equally divided into three meals at 2, 14 and 24 h after birth. After this period, lambs were bottle-fed a commercial milk replacer. Blood plasma sample analysis and BW recordings were carried out before feeding at birth and then at 1, 2, 3, 4, 5 and 20 days after birth. Another blood sample analysis and BW recording was carried out when animals reached 10 kg of BW. During weaning (30 days), sampling was carried out every 5 days. Blood plasma was used to determine the concentrations of IgG and IgM and the complement system activity -total and alternative pathways. The NR group showed greater BW than the C4 and C8 groups during milk feeding period, whereas the C4 and C8 groups had greater BW than the NR group at the end of weaning period. The C8 and NR groups had greater plasma IgG and IgM concentrations than the C4 group during milk feeding period. In addition, C4 and C8 groups showed similar IgG concentrations and greater IgM concentrations than the NR group at the end of the weaning period. Complement system activity was greater in the NR group than in the C4 and C8 groups during the first 3 days after birth. In conclusion, lambs fed amounts of colostrum equivalent to 8 g of IgG/kg of BW showed similar immune variables compared to lambs reared under natural conditions, obtaining a greater BW at the end of the weaning period. Nevertheless, this study shows that not only the colostrum amount but also the management during the milk feeding and weaning period, such as stress produced by dam separation, milk quality and suckling frequency, can affect the final immune status of lambs.Keywords: immune, lamb, colostrum, weaning, artificial rearing ImplicationsColostrum plays a fundamental role in the immunization of newborn ruminants. Artificial rearing is a common method used in dairy farms, increasing the amount of milk for processing. The aim of this study was to feed newborn lambs colostrum with two different IgG concentrations and to compare these animals to natural dam fed lambs. This study showed that administration of 8 g of immunoglobulin g/kg BW at birth, equally divided into three colostrum meals (2, 14 and 26 h), achieved higher circulating immunoglobulin G concentration when compared to the natural rearing treatment, although both artificial rearing groups decreased BW after birth. IntroductionThe relationship between colostrum and the survival of newborn ruminants has been long characterized (Argüello et al., 2004;Castro et al., 2011;Abdou et al., 2014)...

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“…It also plays an important role in determining the concentration of IgG in the colostrum (Brujeni et al, 2010;Kacskovics, 2004;Baintner, 2007;Lerias et al, 2014). The expression of FcRn receptor increased in dry ewes, during late gestation period, and decreased during colostrogenesis (i.e., transfer of Igs from ewes' blood circulation into the colostrum, which occurs in the last two weeks before parturition and lactation period) (Hine et al, 2010;Hernandez-Castellano et al, 2014;Brujeni et al, 2010, Rudovsky et al, 2008Weaver et al, 2000), and Fc portion of IgG is involved in this transport (Micusan and Borduas, 1975). It is concluded here that vaccinating ewes during pregnancy period is very efficient, it helped in boosting Igs production significantly (P<0.05) in the blood and helped in the production of high quality colostrum.…”

Section: Discussionmentioning

confidence: 99%

Occurrence Patterns and Population Density of Barking Deer (Muntiacus Vaginalis) in the Southern Slopes of Himalaya Foothills, Punjab, Pakistan

2020

THE JAPS

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A serious problem in the sheep industry of Kuwait is the high mortality rate of newborn lambs especially during the first three weeks of age. The present study was carried out with the objective to improve the existing vaccination protocol of ewes in the farms of Kuwait, to boost ewe's immunity to produce high quality colostrum. The required baseline data of mortality of young lambs were collected by intensive survey work. Survey studies showed that the mortality rate of young lambs ranged between 30-50% in the sheep farms of Kuwait. Results of field experiment showed that the concentration of Igs of serum and colostrum collected from vaccinated pregnant ewes during pregnancy period was significantly higher (P<0.05) than the rest of the farms where no vaccination was made during pregnancy, and reached 45.79±0.561mg/ml and 65.9±0.805mg/ml in the serum and colostrum, respectively. In addition, the main causes of lambs' mortality were diagnosed as due to the infections by; Clostridia and Pasteurella. From the present study it is concluded that vaccinating ewes during pregnancy period, resulted in significantly higher (P<0.05) secretion of Igs in ewes' blood and colostrum, which resulted into a positive effect on decreasing the mortality rate of young lambs, and is considered very beneficial to livestock-industry-in-Kuwait.

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Passive immune transfer in fat-tailed sheep: Evaluation with different methods

Cited by 11 publications

References 12 publications

Kuzularda Serum ve Kolostral IgG (Pasif İmmünite) Konsantrasyonlarının Total Protein ve Sağlık İle İlişkisi

Kuzularda Serum ve Kolostral IgG (Pasif İmmünite) Konsantrasyonlarının Total Protein ve Sağlık İle İlişkisi

The effect of colostrum period management on BW and immune system in lambs: from birth to weaning

Occurrence Patterns and Population Density of Barking Deer (Muntiacus Vaginalis) in the Southern Slopes of Himalaya Foothills, Punjab, Pakistan

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