2018
DOI: 10.1164/rccm.201712-2606oc
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Passive Nocturnal Physiologic Monitoring Enables Early Detection of Exacerbations in Children with Asthma. A Proof-of-Concept Study

Abstract: Nocturnal physiologic changes correlate with asthma symptoms, supporting the notion that nocturnal physiologic monitoring represents an objective diagnostic tool capable of longitudinally assessing disease control and predicting asthma exacerbations in children with asthma at home.

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Cited by 47 publications
(54 citation statements)
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“…However, subjects also had infrequent episodes (median of three, over up to 2 years) when their RHR increased by more than two standard deviations above their average RHR. While we have no clinical data and thus cannot associate these episodes with any changes in health, others have found that increases in RHR preceded a formal diagnosis of acute infection and asthma exacerbations [30,31]. From these early studies, it is worth considering that a rising RHR may serve as an early warning sign of a physiologic change.…”
Section: Discussionmentioning
confidence: 87%
“…However, subjects also had infrequent episodes (median of three, over up to 2 years) when their RHR increased by more than two standard deviations above their average RHR. While we have no clinical data and thus cannot associate these episodes with any changes in health, others have found that increases in RHR preceded a formal diagnosis of acute infection and asthma exacerbations [30,31]. From these early studies, it is worth considering that a rising RHR may serve as an early warning sign of a physiologic change.…”
Section: Discussionmentioning
confidence: 87%
“…There have been a variety of bed, chair, and other sensors proposed to capture the BCG; several are now available commercially [4][5][6][7][8][9][10][11][12][13][14][15][16][17]. Much of this work has focused on monitoring heart rate along with respiration rate from the accompanying respiration signal, and other parameters for tracking sleep quality.…”
Section: Introductionmentioning
confidence: 99%
“…Researchers in (Huffaker et al, 2018) said that detecting the asthma at an early stage is a big challenge. They have used the random forest machine learning model to predict the asthma exacerbation in the children.…”
Section: Resultsmentioning
confidence: 99%