Passive smoking acutely affects the microcirculation in healthy non-smokers

Linardatou, Vasiliki; Karatzanos, Eleftherios; Panagopoulou, Niki; Delis, Dimitrios; Kourek, Christos; Rovina, Nikoletta; Nanas, Serafim; Vasileiadis, Ioannis

doi:10.1016/j.mvr.2019.103932

Cited by 5 publications

(3 citation statements)

References 48 publications

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“…[ 127 ]. In healthy non-smokers, a 30 min passive exposure to smoking decreases the rate of oxygen consumption and the reperfusion after vascular occlusion and the capillary blood flow is significantly decreased [ 128 , 129 ]. In experiments conducted on the extensor digitorum longus, the chronic adaptation to hypoxia related to the blockade of hemoglobin with carbon monoxide and vasoconstriction, diminished the volume of the muscle fibers II, and increased the fiber oxidative enzyme activity [ 130 ].…”

Section: Insulin Resistance Dyslipidemia Inflammatory and Oxidative M...mentioning

confidence: 99%

The Pathological Links between Adiposity and the Carpal Tunnel Syndrome

Oțelea

Nartea

Popescu

et al. 2022

CIMB

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Many epidemiological studies show support for an association between obesity and carpal tunnel syndrome. Therefore, there is a need to evaluate the physiopathological links that could explain the association between these two entities. Ectopic adipose tissue is responsible for metabolic syndrome and inflammation, and is a major risk factor for diabetes and cardiovascular diseases. Taking these elements into consideration, we conducted an extensive literature revision of the subject, considering as ectopic fat-related mechanisms the following: (a) the direct compression and the association with the metabolic syndrome of the fat deposition around the wrist, (b) the insulin resistance, dyslipidemia, inflammatory, and oxidative mechanisms related to the central deposition of the fat, (c) the impaired muscle contraction and metabolism related to myosteatosis. Each section presents the cellular pathways which are modified by the ectopic deposition of the adipose tissue and the impact in the pathogeny of the carpal tunnel syndrome. In conclusion, the experimental and clinical data support the epidemiological findings. Efforts to reduce the obesity epidemics will improve not only cardio-metabolic health but will reduce the burden of the disability-free life expectancy due to the carpal tunnel syndrome.

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Section: Insulin Resistance Dyslipidemia Inflammatory and Oxidative M...mentioning

confidence: 99%

The Pathological Links between Adiposity and the Carpal Tunnel Syndrome

Oțelea

Nartea

Popescu

et al. 2022

CIMB

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“…Second-hand smoke will be diluted when sidestream smoke and mainstream smoke mix with air and the concentration of tobacco smoke components will settle on the surface of the room to form transformed chemically. 14 Active smokers inhale mainstream smoke, which is smoke drawn directly through the tip of the cigarette.…”

Section: The Difference Between Passive Smokers and Active Smokersmentioning

confidence: 99%

“…Smoking patterns over a long period can cause the cumulative dose of toxic components in the body to be very high. 14…”

Section: The Difference Between Passive Smokers and Active Smokersmentioning

confidence: 99%

Correlation Epidermal Growth Factor Receptor Mutation with Non-small Cell Lung Cancer in Passive Smokers: A Review

Prameswari

Suryandari

2022

Bioscmed

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Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with an extracellular epidermal growth factor binding domain and an intracellular tyrosine kinase domain through signaling pathways to regulate cellular proliferation. Epidermal growth factor receptor binding to its ligand will result in autophosphorylation by intrinsic tyrosine kinase activity, thereby triggering multiple signal transduction cascades. Constant or sustained activation of these downstream target sequences is thought to result in a more aggressive tumor phenotype. Mutations in EGFR are associated with non-small cell lung cancer in passive smokers.

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