“…Comparative histological studies have confirmed the abnormalities in the muscles and nerve plexus (Becker,1976).The anatomical alterations are accompanied functionally by the formation of"segmental high pressure chambers"as described by Reifferscheid(1967).These are formed by extreme haustration and lead to high segmental pressure which Parks and Connel(1969)were able to demonstrate by open-end catheterization. Slack(1962)and Reiffersheid(1967)drew particular attention to changes in the vascular course which occur with advancing age and are simultaneously accompanied by a reduction of connective tissue.…”