Pathogenese und Klinik der Rosazea als Schlüssel für eine symptomorientierte Therapie

Reinholz, Markus; Ruzicka, Thomas; Steinhoff, Martin; Schaller, Martin; Gieler, Uwe; Schöfer, Helmut; Homey, Bernhard; Lehmann, Percy; Luger, T A

doi:10.1111/ddg.13139_g

Cited by 6 publications

(6 citation statements)

References 77 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Since 2017, the ROSacea COnsensus Panel has recommended classification according to symptoms, These are categorized into diagnostic symptoms, major symptoms, and minor symptoms [3,16,17]. This categorization is modular and flexible and thus much better reflects clinical reality.…”

Section: Classification According To Phenotypesmentioning

confidence: 99%

S2k guideline: Rosacea

Clanner‐Engelshofen¹,

Bernhard²,

Dargatz³

et al. 2022

J Deutsche Derma Gesell

View full text Add to dashboard Cite

This updated and upgraded S2k guideline deals with the diagnosis and treatment of rosacea, which is a common, chronic inflammatory skin disease mostly affecting the face. Initially, rosacea is characterized by recurrent erythema, telangiectasia and flushing. Later, the inflammatory component predominates, with persistent erythema with follicular papules, papulopustules and pustules. The development of phyma, which usually occurs on the acral localizations, is the most severe manifestation. For the treatment of rosacea, the interdisciplinary guideline committee, with representatives of the German Dermatological Society (DDG), the Professional Association of German Dermatologists (BVDD), the German Opthalmological Society (DOG), the Society for Dermopharmacy (GD), the Swiss Society for Dermatology and Venereology (SGDV) and the German Rosacea Aid e. V., recommends the avoidance of trigger factors and topical applications of metronidazole, azelaic acid or ivermectin. For

show abstract

Section: Classification According To Phenotypesmentioning

confidence: 99%

S2k guideline: Rosacea

Clanner‐Engelshofen¹,

Bernhard²,

Dargatz³

et al. 2022

J Deutsche Derma Gesell

View full text Add to dashboard Cite

show abstract

“…Seit 2017 empfiehlt das ROSacea COnsensus Panel die Einteilung anhand der Symptome, welche in diagnostische, Major-und Minor-Symptome (beziehungsweise Haupt-und Nebensymptome) unterteilt werden [3,16,17]…”

Section: Einteilung Nach Phänotypenunclassified

“…Seit 2017 empfiehlt das ROSacea COnsensus Panel die Einteilung anhand der Symptome, welche in diagnostische, Major‐ und Minor‐Symptome (beziehungsweise Haupt‐ und Nebensymptome) unterteilt werden [3, 16, 17]. Diese Einteilung ist modular und flexibel, wodurch die klinische Realität weitaus besser abgebildet werden kann.…”

Section: Klinikunclassified

S2k‐Leitlinie: Rosazea

Clanner‐Engelshofen

Bernhard

Dargatz³

et al. 2022

J Deutsche Derma Gesell

View full text Add to dashboard Cite

Die vorliegende aktualisierte und auf S2k-Niveau angehobene Leitlinie befasst sich mit der Diagnostik und der Therapie der Rosazea, bei welcher es sich um eine häufige, chronisch-entzündliche Hauterkrankung handelt, die meist das Gesicht betrifft. Der Verlauf der Rosazea ist initial durch rezidivierende Erytheme, Teleangiektasien sowie Flushing gekennzeichnet. Später überwiegt die entzündliche Komponente, wobei es zu persistierenden Erythemen mit follikulären Papeln, Papulopusteln und Pusteln kommt. Die Bildung von Phymen, die meist an den Akren auftreten, stellt dabei die schwerste Ausprägung der Erkrankung dar. Zur Behandlung empfiehlt die interdisziplinäre Leitlinienkommission, die aus Vertretern der Deutschen Dermatologischen English online version on Wiley Online Library

show abstract

“…Rosacea is a chronic inflammatory disease of the facial skin with a complex etiology and a severe impact on life quality of affected individuals 1–3 . The disease may involve the eyes yet escape diagnosis for a long time, resulting in inappropriate treatment 4,5 .…”

Section: Introductionmentioning

confidence: 99%

“…Rosacea is a chronic inflammatory disease of the facial skin with a complex etiology and a severe impact on life quality of affected individuals. [1][2][3] The disease may involve the eyes yet escape diagnosis for a long time, resulting in inappropriate treatment. 4,5 Many hypotheses have been proposed regarding the complex association of ocular and cutaneous lesions, but all are speculative.…”

Section: Introductionmentioning

confidence: 99%

Clinical clues to identify patients with ocular rosacea – a Germany‐wide epidemiologic analysis

et al. 2022

View full text Add to dashboard Cite

Background and objectives Ocular rosacea is a special manifestation of rosacea with unknown etiology. Eye involvement in rosacea patients is surprisingly common; however, it is often underdiagnosed, resulting in inappropriate treatment. We aimed to provide an updated epidemiologic perspective on ocular rosacea in Germany to improve patient care.Patients and methods Data of 777 rosacea patients were assessed using a detailed online questionnaire regarding ocular and skin symptoms, previous dermatological and ophthalmological consults, presence of type 1 hypersensitivities, and Demodex testing. All data were statistically analyzed.Results Most patients reported ocular symptoms (399/777, 51.4%), including red eyes (179/399, 44.9%), itching (187/399, 46.9%), sty or chalazion (309/399, 77.4%), and dryness (108/399, 27.1%). Ocular rosacea was confirmed in 149/309 cases who consulted an ophthalmologist (45.3%). A total of 159/399 (39.8%) had no pre-existing allergies. Eye involvement was significantly associated with the presence of skin symptoms (P < 0.05), impacting patients' general well-being and overall treatment satisfaction. About half of Demodex-positive patients (21/45, 46.7%) showed ocular symptoms. Conclusions Eye involvement in rosacea patients was common, often presenting with unspecific symptoms.

show abstract

Pathogenese und Klinik der Rosazea als Schlüssel für eine symptomorientierte Therapie

Cited by 6 publications

References 77 publications

S2k guideline: Rosacea

S2k guideline: Rosacea

S2k‐Leitlinie: Rosazea

Clinical clues to identify patients with ocular rosacea – a Germany‐wide epidemiologic analysis

Contact Info

Product

Resources

About