2024
DOI: 10.1111/1348-0421.13160
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Pathogenicity of genotype 2.1 classical swine fever virus isolated from Japan in 2019 in pigs

Maiko Yamashita,
Shoko Iwamoto,
Mariko Ochiai
et al.

Abstract: Classical swine fever (CSF) re‐emerged in Japan in 2018 for the first time in 26 years. The disease has been known to be caused by a moderately pathogenic virus, rather than the highly pathogenic virus that had occurred in the past. However, the underlying pathophysiology remains unknown. This study conducted an experimental challenge on specific pathogen‐free (SPF) pigs in a naïve state for 2, 4, and 6 weeks and confirmed the disease state during each period by clinical observation, virus detection, and patho… Show more

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