2024
DOI: 10.1002/cne.25596
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Pathologic classification of a late‐onset peripheral neuropathy in a spontaneous Labrador retriever dog model

Ryan S. Anderson,
Alexander K. Chu,
Helena Rylander
et al.

Abstract: Late‐onset peripheral neuropathy (LPN) is a heritable canine neuropathy commonly found in Labrador retrievers and is characterized by laryngeal paralysis and pelvic limb paresis. Our objective was to establish canine LPN as a model for human hereditary peripheral neuropathy by classifying it as either an axonopathy or myelinopathy and evaluating length‐dependent degeneration. We conducted a motor nerve conduction study of the sciatic and ulnar nerves, electromyography (EMG) of appendicular and epaxial musculat… Show more

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