Pathological, rickettsiological and immuno‐fluorescence studies of a case of Q fever endocarditis

A case of non-bacterial endocarditis due to Q fever

“…The first report of Q fever as a cause of fatal nonbacterial endocarditis was by Robson and Shimmin (1959). To date eight such cases have been reported from this country (Robson and Shimmin, 1959;Evans, Powell, and Burrell, 1959;Smith and Evans, 1960;Ferguson, Craik, and Grist, 1962;Postgraduate Medical School, 1963;and Mitchell, Grist, Bazaz, and Kenmuir, 1966). We report another case of chronic Q fever which presented a problem of endocarditis with negative blood cultures.…”

Q fever endocarditis

“…(All 16 patients in the recent series had evidence of spread to the liver.) The disease is, indeed, a generalised infection, and C burneti can be isolated not only from the vegetations on the heart valves12-16 but from the blood,13 16 liver 17 18 and spleen also.12 14 18 19 In other reports the disease was found to affect the aortic valve more often than the mitral valve,20 21 but Turck et al found that the mitral valve was affected in more than half their patients. Cardiac failure was common and was probably due in some cases to myocarditis-a rare but recognised complication of acute Q fever.…”

Επιδημιολογικη Ανοσιολογικη Και Κλινικη Ερευνα Ρικετσιωσεων Και Νεο- Ρικετσιωσεων Εν Ελλαδι

“…α) Τού καρδιαγγειακού συστήματος: περικαρδίτιδος, μυοκαροίτιδος, ενδοκαρδίτιδος, βαλβιδοπα'θειών, έμφράκτου μυοκαρδίου, θρομβοαρτηρίτιδος, κλπ. (Woodward καί Bland 1944, Worms 1956, Bernard et al 1959, Bernard et al 1959, Michon et al 1959, Armand et Foliguet 1960, Grist 1963, Nicolau 1963, Mitchell et al 1966., Payzin et. Alt au 1966, Herreman 1968).…”