Pathological vestibular symptoms presenting in a group of adults with HIV/AIDS in Johannesburg, South Africa

Khoza-Shangase, Katijah; Rie, Kayla Jade Van

doi:10.4102/sajid.v32i2.53

Cited by 7 publications

(4 citation statements)

References 22 publications

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“…Evidence linking these HIV treatments to ototoxicity demonstrates that the ototoxic effects create a burden and a distinctive challenge to the provision of ear-and-hearing health care service delivery in South Africa (HPCSA 2018;Hollander, Joubert & Schellack 2020;Khoza-Shangase 2010a; Khoza-Shangase & Masondo 2020; Khoza-Shangase & Prodromos 2021; Khoza-Shangase & Van Rie 2017;. The evidence further supports the development and implementation of systematic and standardised ototoxicity monitoring protocols, such as the ototoxicity grading system within a mobile app for resource-limited settings that are recommended by Hollander et al (2020).…”

Section: Delving Into Ototoxicitymentioning

confidence: 99%

Tele-audiology and preventive audiology: A capacity versus demand challenge imperative in South Africa

Khoza-Shangase¹,

Sebothoma²

2022

Preventive Audiology: An African Perspective

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Peer review declarationThe publisher (AOSIS) endorses the South African 'National Scholarly Book Publishers Forum Best Practice for Peer Review of Scholarly Books'. The manuscript underwent an evaluation to compare the level of originality with other published works and was subjected to rigorous two-step peer review before publication, with the identities of the reviewers not revealed to the editor(s) or author(s). The reviewers were independent of the publisher, editor(s), and author(s). The publisher shared feedback on the similarity report and the reviewers' inputs with the manuscript's editor(s) or author(s) to improve the manuscript. Where the reviewers recommended revision and improvements, the editor(s) or author(s) responded adequately to such recommendations. The reviewers commented positively on the scholarly merits of the manuscript and recommended that the manuscript be published. v Research justificationPreventive health care, where preventive audiology is positioned, contains strategies adopted and implemented for disease and disorder prevention. Hearing function can be negatively impacted by numerous factors, including lifestyle choices, environmental factors, genetic predisposition, the burden of disease and other causes. Frequently, hearing impairment can be prevented and its consequences significantly minimised by preventive measures. Such prevention commands conscientiously deliberate anticipatory actions that can fall under primordial, primary, secondary or tertiary levels of prevention. South Africa, as a resource-constrained low-and middle-income country (LMIC), still has a challenge of high numbers of individuals with preventable hearing impairment from the cradle to the grave. Numerous strategies exist for the prevention of hearing impairment across all ages and in various contexts. Preventive Audiology: An African Perspective is an original scholarly book that introduces the concept of preventive audiology, with a specific focus on the African context, which is in line with the South African re-engineered primary health care strategy and the World Health Organization's approach. The book reflects on contextually relevant and responsive evidence-based perspectives, grounded in an African context on preventive audiology, in four major ear-and-hearing burdens of disease within the South African context, namely, (1) early hearing detection and intervention (EHDI), (2) middle ear pathologies, (3) ototoxicity and (4) noise-induced hearing loss (NIHL). The book represents innovative research, seen from both South African and global perspectives. It offers new discourse and argues for a paradigm shift in how audiology is theorised and performed, particularly in LMIC contexts. The goal of this book is to motivate for a paradigm shift in how ear-and-hearing health care is approached within this LMIC context, while also arguing for Afrocentric best practice evidence that leads to next practice. For Afrocentric epistemology, which is a different narrative that is deliberately removed from Western epi...

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Section: Delving Into Ototoxicitymentioning

confidence: 99%

Tele-audiology and preventive audiology: A capacity versus demand challenge imperative in South Africa

Khoza-Shangase¹,

Sebothoma²

2022

Preventive Audiology: An African Perspective

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“…Identificar a presença, a gravidade e a natureza das manifestações vestibulares em pacientes com HIV / AIDS é de vital importância para os profissionais de saúde, pois os sintomas vestibulares podem ser debilitantes e afetar negativamente a qualidade de vida (Shangase 2017;Holmes & Padgham, 2010).…”

Section: Introductionunclassified

“…tenha havido um aumento no número de participantes que relataram vertigem na sessão de avaliação de três meses após o início da HAART, esse número diminuiu para 0% ao longo do tempo em ambos os grupos; o que levantou um índice de suspeita sobre possíveis efeitos colaterais vestibulares precoces no início da HAART.Em concordância com um estudo que incluiu 96 indivíduos avaliados, seis (22%) relataram ter experimentado outros sintomas vestibulares patológicos debilitantes. Os resultados mostram que os sintomas vestibulares patológicos mais comuns foram: vertigem, tontura, desequilíbrio, dores de cabeça, alterações visuais, náuseas e vômitos(Shangase & Rie, 2017). No entanto em uma análise exploratória com pessoas de idade entre 18-65 o rastreamento e a prevenção de quedas podem ser importantes nessa população em idades relativamente jovens, visto que uma grande proporção de PVHIV (idade mediana, <40 anos) relataram quedas anteriores, e demonstraram redução da qualidade óssea(Berner et al, 2019).Acerca disso os dados podem ser comparados com o estudo que conduziu 15 homens idosos afro-americanos sedentários com HIV e sem HIV, através da Escala de Equilíbrio de Berg (BBS) e o Índice de Marcha Dinâmica (DGI),…”

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Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS: Revisão integrativa

Salgueiro

Momensohn-Santos

2022

RSD

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Introdução: Existe a discussão se o HIV/AIDS ou o tratamento antirretroviral é responsável por manifestações clínicas generalizadas envolvendo o sistema auditivo e/ou o sistema vestibular. Objetivo: Realizar revisão integrativa sobre a Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS. Método: Utilizando-se do critério PICOS, para responder à seguinte questão: O HIV/AIDS são responsáveis por manifestações clínicas generalizadas envolvendo o sistema vestibular? A coleta dos dados a partir das bases: Embase/Elsevier; Lilacs; PubMed; Scopus e Web Of Science, no período de 2010 a 2021. Foram incluídos: artigos completos publicados português, inglês e espanhol, estudo caso-controle, estudo de coorte, estudo piloto, com desenho longitudinal e transversal, que relatam alterações otoneurológicas em pessoas vivendo com HIV/AIDS que foram submetidos a exames de vertigem e/ou tontura. Os descritores basearam-se no Decs - Descritores em Ciências da Saúde - e Mesh Terms, na língua inglesa. Foram excluídos os trabalhos: resumos, anais de congressos, relato de casos, estudos que tenham população com idade inferior a 10 anos e superior a 50 anos, artigos sobre HIV associados a outras patologias de base, Artigos de revisão. Resultados: A pesquisa resultou em 735 estudos identificados nas bases de dados e após a aplicação dos critérios de inclusão restaram 14 artigos para a análise descritiva. Conclusão: Após a conclusão desta revisão de literatura foi possível observar que não há consenso na literatura sobre os efeitos do uso da terapia antirretroviral sobre o sistema vestibular de pessoas vivendo com HIV (PVHIV) ou com a síndrome da imunodeficiência (AIDS).

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“… 7 On the contrary, a study that was conducted in South Africa by showed that SCC was the most prevalent of their lung cancer cases. 8 The most common risk factor for lung cancer is cigarette smoking, but in addition, there are others including genetic factors, age, occupational hazards, radon exposure, radiation therapy and second-hand smoke. 9 …”

Section: Introductionmentioning

confidence: 99%

Histopathological characterization of lung tumours at the University Teaching Hospital, Lusaka, Zambia: a pilot study

Tembo¹,

Kayamba²,

Zulu³

2022

Afr H. Sci.

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Background: There are limited data on histological classification of primary lung cancer from sub-Saharan Africa. Furthermore, the time trends of age-truncated incidence rates of lung cancer by histological phenotype in Zambia are also unknown. Objectives: The objective of this study was to determine histological types of lung tumours at the University Teaching Hospital (UTH) in Lusaka, Zambia. Methods: This was a retrospective pilot study of lung tumour biopsies collected from the histopathology laboratory at the UTH over a period of one year. Tissue sections were stained and when seen, lung cancer was classified using standard histological methods. Data were analysed using IBM SSPS version 23. Results: A total of 23 lung cancer tissues were retrieved. Histological types included eleven (47.8%) squamous cell carcinoma (SCC), six (26.1%) adenocarcinoma, two (8.7%) small cell carcinoma, two (8.7%) large cell carcinoma, 1 (4.3%) inflammatory myofibroblastic tumours and 1 (4.3%) pleural pulmonary blastoma. The results showed that the most affected age group was 60-69 years with most of the histological subtype in this age group being SCC. There was no statistically significant difference of histological subtypes across age groups, p=0.12. Conclusion: This study has shown that the most commonly diagnosed type of primary lung cancer is squamous cell carcinoma.More data are needed to further corroborate this observation. Keywords: Lung cancer; histopathology; Zambia.

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Pathological vestibular symptoms presenting in a group of adults with HIV/AIDS in Johannesburg, South Africa

Cited by 7 publications

References 22 publications

Tele-audiology and preventive audiology: A capacity versus demand challenge imperative in South Africa

Tele-audiology and preventive audiology: A capacity versus demand challenge imperative in South Africa

Ocorrência de sinais e sintomas otoneurológicos em pessoas vivendo com HIV/AIDS: Revisão integrativa

Histopathological characterization of lung tumours at the University Teaching Hospital, Lusaka, Zambia: a pilot study

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