Pathology Quiz Case 1

Peculiar findings of orofacial actinomycosis mimicking the clinical appearance of a tumor of the upper gingiva are reported. An 83-year-old man with bleeding of the gingiva visited our hospital. The clinical diagnosis was a benign gingival tumor, and the lesion was surgically removed. Histologically, the excised specimens showed an ulcerative granuloma lesion covered by bacterial colonies consisting of club-shaped filaments. DNA samples were extracted from paraffin sections and examined by polymerase chain reaction (PCR) for Actinomyces species. The PCR products examined by direct DNA sequencing demonstrated the presence of Actinomyces israelii . Finally, a pathological diagnosis was made of a pyogenic granuloma associated with actinomycosis. The PCR method aided the early and exact diagnosis of the paraffin-embedded sample of oral mucosal infectious diseases including actinomycosis.

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Pyogenic granuloma associated with Actinomyces israelii

Kuyama

Fukui

Ochiai

et al. 2018

Journal of Dental Sciences

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Actinomycotic Osteomyelitis of the Mandible Diagnosed Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry: A Case Report

Yamamoto

Takegawa

Taniike

et al. 2018

Journal of Oral and Maxillofacial Surgery

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Actinomicosis del labio, una localización excepcional

Sánchez-Estella

Bordel-Gómez

Cardeñoso-Álvarez

et al. 2009

Actas Dermo-Sifiliográficas

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Pathology Quiz Case 1

Cited by 10 publications

References 0 publications

Pyogenic granuloma associated with Actinomyces israelii

Pyogenic granuloma associated with Actinomyces israelii

Actinomycotic Osteomyelitis of the Mandible Diagnosed Using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry: A Case Report

Actinomicosis del labio, una localización excepcional

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