Pathophysiological alterations of left ventricular myocardial systolic function during normal pregnancy assessed by speckle tracking echocardiography: a prospective cohort echocardiography study

Tryfou, E; Kostakou, Peggy; Kostopoulos, Vassilios S; Olympios, Christoforos; Mihas, Constantinos; Paraskevaidis, Ioannis; Kouris, Nikos T.

doi:10.1007/s10554-022-02682-0

Cited by 4 publications

(1 citation statement)

References 37 publications

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“…Speckle tracking echocardiography (STE) is a method of assessing cardiac function in which an echocardiographic device with the capability of identifying and tracking a certain point in the myocardium with specific echocardiographic characteristics within a block of speckles is used to determine the displacement of this speckle through the cardiac cycle. STE can calculate parameters like longitudinal, radial, or circumferential myocardial strain, global longitudinal strain (GLS), and strain rate [ 6 – 9 ]. However, longitudinal strain is generally believed to be a better predictor for various outcomes than other myocardial strain indices [ 10 , 11 ].…”

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confidence: 99%

Segmental and global longitudinal strain measurement by 2-dimensional speckle tracking echocardiography in severe rheumatic mitral stenosis

Mehrabi-Pari,

Nayebirad,

Shafiee

et al. 2023

BMC Cardiovasc Disord

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Background The present study aimed to detect subtle left ventricular (LV) dysfunction in patients with severe rheumatic mitral stenosis (MS) by measuring global and segmental longitudinal strain with a two-dimensional speckle tracking echocardiography (2D-STE) method. Methods In this case-control study, 65 patients with severe rheumatic MS and preserved ejection fraction (EF ≥ 50% measured by conventional echocardiographic methods) were compared with 31 otherwise healthy control subjects. All patients underwent LV strain measurement by the 2D-STE method in addition to conventional echocardiography using a VIVID S60 echocardiography device. Results Absolute strain values in myocardial segments 1–8, 10, and 12 (all basal, mid anterior, mid anteroseptal, mid inferior, and mid anterolateral segments) were significantly lower in patients with severe MS compared with the control group (P < 0.05 for all). The absolute global longitudinal strain (GLS) value was higher in the control group (-19.56 vs. -18.25; P = 0.006). After adjustment for age, gender, and systolic blood pressure, the difference in GLS between the two groups was as follows: mean difference=-1.16; 95% CI: -2.58–0.25; P = 0.110. Conclusion In patients with severe rheumatic MS and preserved EF, the absolute GLS tended to be lower than healthy controls. Furthermore, the segmental strain values of LV were significantly lower in most of the basal and some mid-myocardial segments. Further studies are warranted to investigate the underlying pathophysiology and clinical implications of this subclinical dysfunction in certain segments of patients with severe rheumatic MS.

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