2012
DOI: 10.5633/amm.2012.0111
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Pathophysiological or Empirical Approach to the Pharmacotherapy of Epilepsy?

Abstract: The knowledge of etiopathogenesis of epilepsy and the therapeutic treatment of this disease has evolved from the mechanistic approach to the time when a lot is known about the pathophisyological basis of this disease, the mechanisms of epileptogenesis and the propagation of seizures.The aim of this review article is to point to some analyses about the ways the understanding of the mechanisms of action of antiepileptic drugs (AEDs) can help with the prediction of the clinical response to AEDs, and, therefore, u… Show more

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