Patient setup and verification for intensity-modulated radiation therapy (IMRT)

Jones, A; Kleiman, M. T.

doi:10.1016/s0958-3947(03)00069-4

Cited by 11 publications

(2 citation statements)

References 7 publications

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“…It is widely accepted that clinical implementation of IMRT necessitates high standards of treatment verification to minimize delivery error (6)(7)(8). This is particularly applicable to tomotherapeutic IMRT (9).…”

Section: Introductionmentioning

confidence: 99%

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

Deng

Huang

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

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Section: Introductionmentioning

confidence: 99%

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

Deng

Huang

et al. 2011

International Journal of Radiation Oncology*Biology*Physics

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“…Although the IMRT provided a probability of better tumor control for locally pancreatic cancer, the organ motion and patient set-up errors during the treatment may affect the radiation dose of organs due to the complex site of OAR surrounding tumor [16]. As a new technique born of the synthesis of all of the above-mentioned advances, stereotactic body radiotherapy (SBRT) is becoming more widespread, and it is probably known as a promising method of radiotherapy for pancreatic cancer with greater normal tissue sparing [17,18,19,20].…”

Section: Introductionmentioning

confidence: 99%

CyberKnife and EDGE in stereotactic body radiotherapy for pancreas cancer: a comparison of plan quality

Dai¹,

Ma²,

Cao³

et al. 2020

Preprint

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Purpose: To perform a comprehensive comparison of the different stereotactic body radiotherapy (SBRT) plans between the Varian EDGE and CyberKnife (CK) systems for pancreas cancer.Materials and methods: Fifteen patients with pancreas cancer were selected in this study. The median planning target volume (PTV) was 28.688cm 3 (5.736 to 49.246 cm 3 ). The SBRT plans for the EDGE and CK were generated in the Eclipse and Multiplan systems respectively with the same contouring and dose constrains for PTV and organ at risk (OAR). Dose distributions in PTV were evaluated in terms of coverage, conformity index (CI), new conformity index (nCI), homogeneity index (HI), and gradient index (GI). OARs, including spinal cord, bowel, stomach, duodenum and kidneys were statistically evaluated by different dose-volume metrics and equivalent uniform dose (EUD) . The volume covered by the different isodose lines (ISDL) ranging from 10% to 100% for normal tissue were also analyzed.Results: All SBRT plans for EDGE and CK met the clinical requirement for PTV and OARs. . For the PTV, the dosimetric metrics in EDGE plans were lower than that in CK, except that D 99 and GI were slightly higher. The EDGE plans with lower CI , nCI and HI were superior to offer the better conformity and homogeneity for PTV. For the normal tissue, the CK plans were better at OARs sparing. The radiobiological indices EUD of spinal cord, duodenum, stomach, and kidneys were lower for CK plans, except that liver were higher. The volumes of normal tissue covered by medium ISDLs (with range of 20%~70%) were lower for CK plans while that covered by high and low ISDLs were lower for EDGE plans.Conclusions: This study indicated that both EDGE and CK generated equivalent plan quality, and both systems can be considered as beneficial techniques for SBRT of pancreas cancer. EDGE plans offered the better conformity and homogeneity of dose distributions for PTV, while the CK plans could minimize the exposure of OARs.

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Physikalische Grundlagen

Hartmann

Schlegel

Strahlentherapie

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Patient setup and verification for intensity-modulated radiation therapy (IMRT)

Cited by 11 publications

References 7 publications

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

CyberKnife and EDGE in stereotactic body radiotherapy for pancreas cancer: a comparison of plan quality

Physikalische Grundlagen

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Patient setup and verification for intensity-modulated radiation therapy (IMRT)

Cited by 11 publications

References 7 publications

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

Real-Time In Vivo Dosimetry With MOSFET Detectors in Serial Tomotherapy for Head and Neck Cancer Patients

CyberKnife and EDGE in stereotactic body radiotherapy for pancreas cancer: a comparison of plan quality﻿

Physikalische Grundlagen

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Product

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CyberKnife and EDGE in stereotactic body radiotherapy for pancreas cancer: a comparison of plan quality