Pattern & presentation of colorectal cancer in central Sudan, a retrospective descriptive study, 2010-2012.

Abstract

Aims & objective: To determine the age and gender distribution and clinical presentation of patients together with histological types of colorectal cancer cases presented to Ibn Sina specialized hospital. Patients and methods: This retrospective study was conducted in Ibn Sina Hospital (Sudan). Seventy three (73) patients of colorectal cancer who presented in the period from January 2010 to December 2012 were included. Data were collected from their hospital records and analyzed using SPSS computer program 17. Results: More than 17 % of the study populations was below the age of 40 years, and 43.84% was below 50 years. The male to female ratio was 1:1.02. Rectal bleeding is the commonest presenting symptom and well differentiated adenocarcinoma is the dominating tumor grade. 8.3 % of patients presented with liver metastasis. Conclusion: Colorectal cancer in this study was found more in young age groups with a peak frequency at the fifth and sixth decades.

Current Patterns of Colorectal Carcinoma: Retrospective Evaluation of Cases

“…11 However, Taha et al, also reported rectal bleeding to be the most common presenting symptom accounting for 71.7% and a study conducted in Wad Medani Hospital in Sudan described rectal bleeding as the most common presenting symptom in 97.2% patients. 12 In our study however, none of the patients presented with tenesmus as the presenting symptom but in many studies tenesmus was one of the chief complaints in the patients with colorectal carcinoma. A study conducted in Sudan by Taha et al, shows that around 32% patients had tenesmus.…”

“…A study conducted in Sudan by Taha et al, shows that around 32% patients had tenesmus. 12 Abdalla et al however in his study reported that of 35% of the patients who presented in the emergency department, 94.8% had an acute or sub acute intestinal obstruction. 13 In conclusion, colorectal cancer was found to affect younger age groups, but with the peak incidence in patients above the age of 45 years.…”

“…Near similar findings were reported by Taha et al in his study in Sudan where he reported positive family history in the 15% of the patients. 12 Another study conducted by Moris et al in United Kingdom reported that family history accounted for 15.7 % of the population that was made part of the study. 15 Our study showed that the most common presenting symptom in the patients was Hematochezia (16.5%) while constipation being the next most common symptom accounting for 14%.…”

“…These findings were supported by another study conducted by Verschueren RC et al and a study conducted in Sudan by Taha et al, where the ratio of male to female were found to be 1:1.02. 12 However, Ahmed Gato et al, reported a greater incidence with the male to female ratio of 2.5: 1. 11…”

“…11 CRC affects men and women of all racial and ethnic groups, and is most often found in people aged 50 years or older in developed countries. 12 The incidence of CRC in developing countries such as; Pakistan is increasing to an alarming levels and that too in the younger age groups.…”