“…5). In addition, fusion-relevant proteins also participate in a number of other developmental processes such as muscle attachment (Schröter et al, 2004;Schä fer et al, 2007), sarcomere assembly (e.g., Kreisköther et al, 2006) and visceral fusion (Klapper et al, 2001(Klapper et al, , 2002San Martin and Bate, 2001), Malpighian tubule organization (Denholm et al, 2003;Pü tz et al, 2005), garland cell development (Weavers et al, 2009), as well as eye development (e.g., Carthew, 2007;Fischbach et al, 2009). Thus, because of the multifunctional roles of fusion-relevant proteins, care should be taken when interpreting biochemical protein interaction assays, and the findings need to be correlated to the particular biological function.…”